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snd1 protein (Schizosaccharomyces pombe) - STRING interaction network
"snd1" - Staphylococcal nuclease domain-containing protein 1 in Schizosaccharomyces pombe
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Predicted Interactions
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textmining
co-expression
protein homology
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snd1Staphylococcal nuclease domain-containing protein 1; RNA-binding protein, involved in chromatin silencing by small RNA, Snd1 (878 aa)    
Predicted Functional Partners:
ago1
Protein argonaute; Required for G1 arrest and mating in response to nitrogen starvation. Ago1 regulation of cytokinesis and cell cycle checkpoints occurs downstream of dcr1. Required, indirectly, for regulated hyperphosphorylation of cdc2. Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation, accurate chromosome segregation, centromere cohesion and telomere function during mitosis and meiosis. Required for silencing at the centromeres and for initiation of transcriptionally silent heterochromatin at the mating type locus. Promotes histone H [...] (834 aa)
     
  0.955
sgf29
SAGA-associated factor 29; Chromatin reader component of the transcription regulatory histone acetylation (HAT) complex SAGA. Sgf29 specifically recognizes and binds methylated ’Lys-4’ of histone H3 (H3K4me), with a preference for trimethylated form (H3K4me3). In the SAGA complex, sgf29 is required to facilitate crosstalk between gcn5 acetyltransferase activity and H3K4me3 recognition. At the promoters, SAGA is required for recruitment of the basal transcription machinery. It influences RNA polymerase II transcriptional activity through different activities such as TBP interaction and [...] (244 aa)
       
 
  0.894
sec61
Protein transport protein sec61 subunit alpha; Appears to play a crucial role in the insertion of secretory and membrane polypeptides into the ER. It is required for assembly of membrane and secretory proteins and is essential for cell growth. It interacts with other membrane proteins required for protein translocation. Upon binding to sec62/63 complex, secretory precursor polypeptides may engage sec61 to begin membrane penetration event. A cycle of assembly and disassembly of sec62/63 from sec61 may govern the activity of the translocase (By similarity) (479 aa)
     
        0.876
SPBC19G7.17.1
Uncharacterized protein C19G7.17; Translocon subunit Sec61 homolog (predicted) (475 aa)
     
        0.870
ost1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Essential subunit of the N-oligosaccharyl transferase (OST) complex which catalyzes the transfer of a high mannose oligosaccharide from a lipid-linked oligosaccharide donor to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains (450 aa)
     
      0.795
dcr1
Protein Dicer; Required for G1 arrest and mating in response to nitrogen starvation. Ago1 regulation of cytokinesis and cell cycle checkpoints occurs downstream of dcr1. Required, indirectly, for regulated hyperphosphorylation of cdc2 (1374 aa)
     
 
  0.782
skb1
Protein arginine N-methyltransferase skb1; S-adenosyl-L-methionine-dependent protein-arginine N- methyltransferase that can catalyze both the mono- and symmetric (type II) dimethylation of the guanidino nitrogens of arginine residues in target proteins (By similarity). Positively modulates the shk1 kinase function. May be a mediator of hyperosmotic stress response (645 aa)
     
   
  0.772
chp1
Chromo domain-containing protein 1; Component of the kinetochore which plays a role in stabilizing microtubules and so allowing accurate chromosome segregation. Has a role in the RNA interference (RNAi) pathway which is important for heterochromatin formation and accurate chromosome segregation. A member of the RNA-induced transcriptional silencing (RITS) complex which is involved in the biosynthesis of dsRNA from primer siRNAs provided by the RNA- directed RNA polymerase (RDRC) complex (960 aa)
     
  0.772
alp13
Chromatin modification-related protein eaf3; Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of selected genes principally by acetylation of nucleosomal histone H4 and H2A. The NuA4 complex is also involved in DNA repair (By similarity). Also involved in deacetylation of histones, chromatin assembly and chromosome segregation. May act as a transcriptional oscillator, directing histone deacetylases to specific chromosomal domains; Belongs to the MRG family (337 aa)
     
   
  0.760
SPBC4F6.14
RNA-binding protein (predicted) (674 aa)
     
   
  0.744
Your Current Organism:
Schizosaccharomyces pombe
NCBI taxonomy Id: 4896
Other names: CBS 356, CCRC 21461, DBVPG 6277, JCM 8274, MUCL 30245, NRRL Y-12796, S. pombe, Schizosaccharomyces malidevorans, Schizosaccharomyces pombe, fission yeast
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