node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DKAM_0210 | DKAM_0296 | DKAM_0210 | DKAM_0296 | FAD dependent oxidoreductase. | Dihydrolipoamide dehydrogenase. | 0.482 |
DKAM_0210 | DKAM_0297 | DKAM_0210 | DKAM_0297 | FAD dependent oxidoreductase. | Glycine dehydrogenase subunit 2. | 0.929 |
DKAM_0210 | DKAM_0299 | DKAM_0210 | DKAM_0299 | FAD dependent oxidoreductase. | gcvT; glycine cleavage system aminomethyltransferase T; K00605 aminomethyltransferase. | 0.977 |
DKAM_0210 | gcvPA | DKAM_0210 | DKAM_0298 | FAD dependent oxidoreductase. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.922 |
DKAM_0210 | glyA | DKAM_0210 | DKAM_0300 | FAD dependent oxidoreductase. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.933 |
DKAM_0296 | DKAM_0210 | DKAM_0296 | DKAM_0210 | Dihydrolipoamide dehydrogenase. | FAD dependent oxidoreductase. | 0.482 |
DKAM_0296 | DKAM_0297 | DKAM_0296 | DKAM_0297 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase subunit 2. | 0.989 |
DKAM_0296 | DKAM_0299 | DKAM_0296 | DKAM_0299 | Dihydrolipoamide dehydrogenase. | gcvT; glycine cleavage system aminomethyltransferase T; K00605 aminomethyltransferase. | 0.992 |
DKAM_0296 | gcvH | DKAM_0296 | DKAM_0301 | Dihydrolipoamide dehydrogenase. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
DKAM_0296 | gcvPA | DKAM_0296 | DKAM_0298 | Dihydrolipoamide dehydrogenase. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.989 |
DKAM_0296 | glyA | DKAM_0296 | DKAM_0300 | Dihydrolipoamide dehydrogenase. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.969 |
DKAM_0296 | purQ | DKAM_0296 | DKAM_0521 | Dihydrolipoamide dehydrogenase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.820 |
DKAM_0296 | sucC | DKAM_0296 | DKAM_1041 | Dihydrolipoamide dehydrogenase. | succinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.799 |
DKAM_0297 | DKAM_0210 | DKAM_0297 | DKAM_0210 | Glycine dehydrogenase subunit 2. | FAD dependent oxidoreductase. | 0.929 |
DKAM_0297 | DKAM_0296 | DKAM_0297 | DKAM_0296 | Glycine dehydrogenase subunit 2. | Dihydrolipoamide dehydrogenase. | 0.989 |
DKAM_0297 | DKAM_0299 | DKAM_0297 | DKAM_0299 | Glycine dehydrogenase subunit 2. | gcvT; glycine cleavage system aminomethyltransferase T; K00605 aminomethyltransferase. | 0.999 |
DKAM_0297 | gcvH | DKAM_0297 | DKAM_0301 | Glycine dehydrogenase subunit 2. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.999 |
DKAM_0297 | gcvPA | DKAM_0297 | DKAM_0298 | Glycine dehydrogenase subunit 2. | Glycine dehydrogenase subunit 1; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein. | 0.999 |
DKAM_0297 | glyA | DKAM_0297 | DKAM_0300 | Glycine dehydrogenase subunit 2. | Glycine/serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta- hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.987 |
DKAM_0297 | purQ | DKAM_0297 | DKAM_0521 | Glycine dehydrogenase subunit 2. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.837 |