STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdxSPyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. (335 aa)    
Predicted Functional Partners:
pdxT
Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
 0.999
DKAM_0480
Pyridoxal-5'-phosphate-dependent protein beta subunit; Pfam00291, PALP, Pyridoxal-phosphate dependent enzyme.
  
  
 0.907
DKAM_0615
ATP-dependent 6-phosphofructokinase; COG0524 Sugar kinases, ribokinase family; Belongs to the carbohydrate kinase PfkB family.
    
 0.840
DKAM_0837
ATP-dependent 6-phosphofructokinase; COG0524 Sugar kinases, ribokinase family.
    
 0.840
DKAM_0540
Ribose-phosphate pyrophosphokinase; Belongs to the ribose-phosphate pyrophosphokinase family.
  
 
  0.810
DKAM_0464
Ribose 5-phosphate isomerase.
    
  0.803
DKAM_1397
Sugar-phosphate isomerase, RpiB/LacA/LacB family.
   
 
  0.802
DKAM_0012
Phosphomannomutase; Belongs to the phosphohexose mutase family.
     
  0.800
DKAM_0110
Phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I.
     
  0.800
DKAM_0119
Phospho-sugar mutase; Belongs to the phosphohexose mutase family.
     
  0.800
Your Current Organism:
Desulfurococcus amylolyticus
NCBI taxonomy Id: 490899
Other names: D. amylolyticus 1221n, Desulfurococcus amylolyticus 1221n, Desulfurococcus kamchatkensis 1221n, Proteinoruptor kamchatkensis 1221n
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.