node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DKAM_0042 | DKAM_0433 | DKAM_0042 | DKAM_0433 | Cell division control protein 48, AAA family. | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | 0.571 |
DKAM_0042 | DKAM_0862 | DKAM_0042 | DKAM_0862 | Cell division control protein 48, AAA family. | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.809 |
DKAM_0042 | glpK | DKAM_0042 | DKAM_0882 | Cell division control protein 48, AAA family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.762 |
DKAM_0042 | pan | DKAM_0042 | DKAM_1268 | Cell division control protein 48, AAA family. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.624 |
DKAM_0042 | psmA | DKAM_0042 | DKAM_1327 | Cell division control protein 48, AAA family. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.666 |
DKAM_0042 | psmB1 | DKAM_0042 | DKAM_1278 | Cell division control protein 48, AAA family. | Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.661 |
DKAM_0042 | psmB2 | DKAM_0042 | DKAM_1288 | Cell division control protein 48, AAA family. | Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.661 |
DKAM_0181 | DKAM_0433 | DKAM_0181 | DKAM_0433 | AAA family ATPase. | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | 0.571 |
DKAM_0181 | DKAM_0862 | DKAM_0181 | DKAM_0862 | AAA family ATPase. | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.809 |
DKAM_0181 | glpK | DKAM_0181 | DKAM_0882 | AAA family ATPase. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.762 |
DKAM_0181 | pan | DKAM_0181 | DKAM_1268 | AAA family ATPase. | Proteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] | 0.685 |
DKAM_0181 | psmA | DKAM_0181 | DKAM_1327 | AAA family ATPase. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.656 |
DKAM_0181 | psmB1 | DKAM_0181 | DKAM_1278 | AAA family ATPase. | Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.663 |
DKAM_0181 | psmB2 | DKAM_0181 | DKAM_1288 | AAA family ATPase. | Proteasome subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.656 |
DKAM_0433 | DKAM_0042 | DKAM_0433 | DKAM_0042 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Cell division control protein 48, AAA family. | 0.571 |
DKAM_0433 | DKAM_0181 | DKAM_0433 | DKAM_0181 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | AAA family ATPase. | 0.571 |
DKAM_0433 | DKAM_0862 | DKAM_0433 | DKAM_0862 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family. | 0.780 |
DKAM_0433 | DKAM_1033 | DKAM_0433 | DKAM_1033 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Thermosome subunit alpha; COG0459 Chaperonin GroEL (HSP60 family); Belongs to the TCP-1 chaperonin family. | 0.406 |
DKAM_0433 | DKAM_1070 | DKAM_0433 | DKAM_1070 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | AAA family ATPase, CDC48 subfamily. | 0.571 |
DKAM_0433 | glpK | DKAM_0433 | DKAM_0882 | Protease; COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.907 |