node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aflv_2333 | drm | Aflv_2333 | Aflv_0998 | Phosphomannomutase. | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | 0.916 |
Aflv_2333 | pdxS | Aflv_2333 | Aflv_0011 | Phosphomannomutase. | Pyridoxine biosynthesis enzyme PDX1/PDX2, synthetase subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.800 |
Aflv_2333 | pdxT | Aflv_2333 | Aflv_0012 | Phosphomannomutase. | Pyridoxine biosynthesis enzyme PDX1/PDX2, glutaminase subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.800 |
Aflv_2333 | prs | Aflv_2333 | Aflv_0044 | Phosphomannomutase. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.929 |
Aflv_2333 | rbsK | Aflv_2333 | Aflv_2672 | Phosphomannomutase. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.909 |
Aflv_2333 | rpiB | Aflv_2333 | Aflv_2715 | Phosphomannomutase. | Ribose 5-phosphate isomerase. | 0.907 |
Aflv_2333 | tal | Aflv_2333 | Aflv_2728 | Phosphomannomutase. | Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. | 0.826 |
Aflv_2333 | tkt | Aflv_2333 | Aflv_1502 | Phosphomannomutase. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.921 |
dacA | pdxS | Aflv_0010 | Aflv_0011 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Pyridoxine biosynthesis enzyme PDX1/PDX2, synthetase subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.553 |
dacA | pdxT | Aflv_0010 | Aflv_0012 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Pyridoxine biosynthesis enzyme PDX1/PDX2, glutaminase subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.496 |
dacA | serS | Aflv_0010 | Aflv_0013 | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). | 0.423 |
drm | Aflv_2333 | Aflv_0998 | Aflv_2333 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Phosphomannomutase. | 0.916 |
drm | pdxS | Aflv_0998 | Aflv_0011 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Pyridoxine biosynthesis enzyme PDX1/PDX2, synthetase subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.800 |
drm | pdxT | Aflv_0998 | Aflv_0012 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Pyridoxine biosynthesis enzyme PDX1/PDX2, glutaminase subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.800 |
drm | prs | Aflv_0998 | Aflv_0044 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.915 |
drm | rbsK | Aflv_0998 | Aflv_2672 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. | 0.905 |
drm | rpiB | Aflv_0998 | Aflv_2715 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Ribose 5-phosphate isomerase. | 0.912 |
drm | tkt | Aflv_0998 | Aflv_1502 | Phosphopentomutase; Phosphotransfer between the C1 and C5 carbon atoms of pentose; Belongs to the phosphopentomutase family. | Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. | 0.917 |
pdxS | Aflv_2333 | Aflv_0011 | Aflv_2333 | Pyridoxine biosynthesis enzyme PDX1/PDX2, synthetase subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | Phosphomannomutase. | 0.800 |
pdxS | dacA | Aflv_0011 | Aflv_0010 | Pyridoxine biosynthesis enzyme PDX1/PDX2, synthetase subunit; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.553 |