STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
spoIIABStage II sporulation protein AB (anti-sigma factor, Ser/Thr protein kinase); Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition. (146 aa)    
Predicted Functional Partners:
spoIIAA
Stage II sporulation protein AA (antagonist of anti-sigma factor, stand-alone STAS domain); Belongs to the anti-sigma-factor antagonist family.
 
 
 0.996
sigF
RNA polymerase sigma factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
 
 0.990
rsbV
Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor, stand-alone STAS domain).
  
 
 0.990
rsbU
Response regulator with PP2C-type protein phosphatase output domain (REC-PP2C domains).
  
 
 0.981
motA
Flagellar motor protein A.
   
    0.914
Aflv_1736
Uncharacterized conserved protein.
   
    0.914
fliG
Flagellar motor switch protein FliG.
   
    0.914
flgB
Flagellar basal body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
   
    0.914
flgK
Flagellar hook-associated protein.
   
    0.914
spoIIGA
Stage II sporulation protein G (protease).
  
  
 0.906
Your Current Organism:
Anoxybacillus flavithermus
NCBI taxonomy Id: 491915
Other names: A. flavithermus WK1, Anoxybacillus flavithermus WK1, Anoxybacillus flavithermus str. WK1, Anoxybacillus flavithermus strain WK1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.