STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SUB2ATP-dependent RNA helicase SUB2; ATP-binding RNA helicase involved in transcription elongation and required for the export of mRNA out of the nucleus. SUB2 plays also a role in pre-mRNA splicing and spliceosome assembly. May be involved in rDNA and telomeric silencing, and maintenance of genome integrity (By similarity); Belongs to the DEAD box helicase family. DECD subfamily. (433 aa)    
Predicted Functional Partners:
PICST_81261
RNA annealing protein.
   
 0.999
RLR1
THO2 plays a role in transcriptional elongation.
   
 0.997
PICST_35114
RRM domain-containing protein.
   
 0.995
PICST_47344
Cell cycle control protein.
   
 0.979
PICST_41297
Pre-mRNA splicing factor affecting 3 splice site choice.
   
 0.974
MTR4
Dead-box family helicase required for mRNA export from nucleus.
    
 0.974
PICST_67017
Smg4_UPF3 domain-containing protein.
    
 0.973
PICST_29180
WD_REPEATS_REGION domain-containing protein.
   
 0.971
PICST_22536
SAP domain-containing protein.
   
 0.971
PICST_39722
PPIase cyclophilin-type domain-containing protein.
    
  0.970
Your Current Organism:
Scheffersomyces stipitis
NCBI taxonomy Id: 322104
Other names: Pichia stipitis CBS 6054, S. stipitis CBS 6054, Scheffersomyces stipitis CBS 6054
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