node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ASC1 | IF4F1 | A3LWH7 | A3LTW3 | WD repeat protein. | Translation initiation factor 4G. | 0.480 |
ASC1 | PAB1 | A3LWH7 | A3LXL0 | WD repeat protein. | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | 0.464 |
ASC1 | PICST_81210 | A3LWH7 | A3GIA6 | WD repeat protein. | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | 0.605 |
ASC1 | PICST_84007 | A3LWH7 | A3LV28 | WD repeat protein. | RRM domain-containing protein. | 0.537 |
ASC1 | PRT1 | A3LWH7 | A3LY29 | WD repeat protein. | Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 0.985 |
ASC1 | RPL7B | A3LWH7 | A3GFU4 | WD repeat protein. | 60S large subunit ribosomal protein. | 0.999 |
ASC1 | TEF4 | A3LWH7 | A3LPZ2 | WD repeat protein. | Translation elongation factor eEF1 gamma. | 0.974 |
ASC1 | TIF1 | A3LWH7 | A3GFI4 | WD repeat protein. | ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | 0.936 |
ASC1 | TIF34 | A3LWH7 | A3LX18 | WD repeat protein. | Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 0.979 |
ASC1 | TIF4631 | A3LWH7 | A3LTW4 | WD repeat protein. | mRNA cap binding protein eIF 4F. | 0.480 |
IF4F1 | ASC1 | A3LTW3 | A3LWH7 | Translation initiation factor 4G. | WD repeat protein. | 0.480 |
IF4F1 | PAB1 | A3LTW3 | A3LXL0 | Translation initiation factor 4G. | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | 0.966 |
IF4F1 | PICST_81210 | A3LTW3 | A3GIA6 | Translation initiation factor 4G. | Uncharacterized protein; Belongs to the eukaryotic initiation factor 4E family. | 0.996 |
IF4F1 | PICST_84007 | A3LTW3 | A3LV28 | Translation initiation factor 4G. | RRM domain-containing protein. | 0.849 |
IF4F1 | PRT1 | A3LTW3 | A3LY29 | Translation initiation factor 4G. | Eukaryotic translation initiation factor 3 subunit B; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 0.721 |
IF4F1 | TIF1 | A3LTW3 | A3GFI4 | Translation initiation factor 4G. | ATP-dependent RNA helicase eIF4A; ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon (By similarity). | 0.994 |
IF4F1 | TIF34 | A3LTW3 | A3LX18 | Translation initiation factor 4G. | Eukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. | 0.593 |
IF4F1 | TIF4631 | A3LTW3 | A3LTW4 | Translation initiation factor 4G. | mRNA cap binding protein eIF 4F. | 0.930 |
PAB1 | ASC1 | A3LXL0 | A3LWH7 | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | WD repeat protein. | 0.464 |
PAB1 | IF4F1 | A3LXL0 | A3LTW3 | Polyadenylate-binding protein, cytoplasmic and nuclear; Binds the poly(A) tail of mRNA. Appears to be an important mediator of the multiple roles of the poly(A) tail in mRNA biogenesis, stability and translation. In the nucleus, involved in both mRNA cleavage and polyadenylation. Is also required for efficient mRNA export to the cytoplasm. Acts in concert with a poly(A)-specific nuclease (PAN) to affect poly(A) tail shortening, which may occur concomitantly with either nucleocytoplasmic mRNA transport or translational initiation. In the cytoplasm, stimulates translation initiation and [...] | Translation initiation factor 4G. | 0.966 |