node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AI3 | AI4 | Q0060 | Q0065 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | 0.968 |
AI3 | ATP6 | Q0060 | Q0085 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Subunit a of the F0 sector of mitochondrial F1F0 ATP synthase; mitochondrially encoded; translation is specifically activated by Atp22p; ATP6 and ATP8 mRNAs are not translated in the absence of the F1 sector of ATPase; mutations in human ortholog MT-ATP6 are associated with neurodegenerative disorders such as Neurogenic Ataxia and Retinitis Pigmentosa (NARP), Leigh syndrome (LS), Charcot-Marie-Tooth (CMT), and ataxia telangiectasia. | 0.707 |
AI3 | BI2 | Q0060 | Q0110 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Cytochrome b mRNA maturase bI2; Mitochondrial mRNA maturase with a role in splicing; encoded by both exon and intron sequences of partially processed COB mRNA; In the N-terminal section; belongs to the cytochrome b family. | 0.914 |
AI3 | BI4 | Q0060 | Q0120 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | 0.829 |
AI3 | COB | Q0060 | Q0105 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Cytochrome b; mitochondrially encoded subunit of the ubiquinol-cytochrome c reductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p. | 0.894 |
AI3 | COX2 | Q0060 | Q0250 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Subunit II of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits. | 0.892 |
AI3 | COX3 | Q0060 | Q0275 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Subunit III of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits. | 0.933 |
AI3 | COX4 | Q0060 | YGL187C | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Subunit IV of cytochrome c oxidase; the terminal member of the mitochondrial inner membrane electron transport chain; precursor N-terminal 25 residues are cleaved during mitochondrial import; phosphorylated; spermidine enhances translation. | 0.650 |
AI3 | RIP1 | Q0060 | YEL024W | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Ubiquinol-cytochrome-c reductase; a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration; during import, Rip1p is first imported into the mitochondrial matrix where it is processed, acquires its Fe-S cluster, and is folded, then is translocated into the inner membrane by the action of a homo-oligomer of Bcs1p, and finally is delivered by Bcs1p to Complex III for assembly. | 0.540 |
AI3 | SCEI | Q0060 | Q0160 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | I-SceI DNA endonuclease; encoded by the mitochondrial group I intron of the 21S_rRNA gene; mediates gene conversion that propagates the intron into intron-less copies of the 21S_rRNA gene. | 0.865 |
AI4 | AI3 | Q0065 | Q0060 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | 0.968 |
AI4 | ATP6 | Q0065 | Q0085 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Subunit a of the F0 sector of mitochondrial F1F0 ATP synthase; mitochondrially encoded; translation is specifically activated by Atp22p; ATP6 and ATP8 mRNAs are not translated in the absence of the F1 sector of ATPase; mutations in human ortholog MT-ATP6 are associated with neurodegenerative disorders such as Neurogenic Ataxia and Retinitis Pigmentosa (NARP), Leigh syndrome (LS), Charcot-Marie-Tooth (CMT), and ataxia telangiectasia. | 0.978 |
AI4 | BI2 | Q0065 | Q0110 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Cytochrome b mRNA maturase bI2; Mitochondrial mRNA maturase with a role in splicing; encoded by both exon and intron sequences of partially processed COB mRNA; In the N-terminal section; belongs to the cytochrome b family. | 0.975 |
AI4 | BI4 | Q0065 | Q0120 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | 0.975 |
AI4 | COB | Q0065 | Q0105 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Cytochrome b; mitochondrially encoded subunit of the ubiquinol-cytochrome c reductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p. | 0.990 |
AI4 | COX2 | Q0065 | Q0250 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Subunit II of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits. | 0.999 |
AI4 | COX3 | Q0065 | Q0275 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Subunit III of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits. | 0.998 |
AI4 | COX4 | Q0065 | YGL187C | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Subunit IV of cytochrome c oxidase; the terminal member of the mitochondrial inner membrane electron transport chain; precursor N-terminal 25 residues are cleaved during mitochondrial import; phosphorylated; spermidine enhances translation. | 0.967 |
AI4 | RIP1 | Q0065 | YEL024W | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Ubiquinol-cytochrome-c reductase; a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration; during import, Rip1p is first imported into the mitochondrial matrix where it is processed, acquires its Fe-S cluster, and is folded, then is translocated into the inner membrane by the action of a homo-oligomer of Bcs1p, and finally is delivered by Bcs1p to Complex III for assembly. | 0.971 |
AI4 | SCEI | Q0065 | Q0160 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | I-SceI DNA endonuclease; encoded by the mitochondrial group I intron of the 21S_rRNA gene; mediates gene conversion that propagates the intron into intron-less copies of the 21S_rRNA gene. | 0.970 |