node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AI3 | AI4 | Q0060 | Q0065 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | 0.968 |
AI3 | BI4 | Q0060 | Q0120 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | 0.829 |
AI3 | Q0255 | Q0060 | Q0255 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | Uncharacterized mitochondrial protein RF1; Maturase-like protein. | 0.650 |
AI3 | SCEI | Q0060 | Q0160 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | I-SceI DNA endonuclease; encoded by the mitochondrial group I intron of the 21S_rRNA gene; mediates gene conversion that propagates the intron into intron-less copies of the 21S_rRNA gene. | 0.865 |
AI4 | AI3 | Q0065 | Q0060 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | 0.968 |
AI4 | BI4 | Q0065 | Q0120 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | 0.975 |
AI4 | Q0255 | Q0065 | Q0255 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | Uncharacterized mitochondrial protein RF1; Maturase-like protein. | 0.653 |
AI4 | SCEI | Q0065 | Q0160 | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | I-SceI DNA endonuclease; encoded by the mitochondrial group I intron of the 21S_rRNA gene; mediates gene conversion that propagates the intron into intron-less copies of the 21S_rRNA gene. | 0.970 |
BI4 | AI3 | Q0120 | Q0060 | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | 0.829 |
BI4 | AI4 | Q0120 | Q0065 | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | 0.975 |
BI4 | Q0255 | Q0120 | Q0255 | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | Uncharacterized mitochondrial protein RF1; Maturase-like protein. | 0.935 |
BI4 | SCEI | Q0120 | Q0160 | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | I-SceI DNA endonuclease; encoded by the mitochondrial group I intron of the 21S_rRNA gene; mediates gene conversion that propagates the intron into intron-less copies of the 21S_rRNA gene. | 0.860 |
BI4 | URA3 | Q0120 | YEL021W | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | Orotidine-5'-phosphate (OMP) decarboxylase; catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound. | 0.411 |
HO | RAD52 | YDL227C | YML032C | Homothallic switching endonuclease; Site-specific endonuclease; required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p, and Ash1p. | DNA repair and recombination protein RAD52; Protein that stimulates strand exchange; stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis and UV induced sister chromatid recombination; Belongs to the RAD52 family. | 0.907 |
HO | SCEI | YDL227C | Q0160 | Homothallic switching endonuclease; Site-specific endonuclease; required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p, and Ash1p. | I-SceI DNA endonuclease; encoded by the mitochondrial group I intron of the 21S_rRNA gene; mediates gene conversion that propagates the intron into intron-less copies of the 21S_rRNA gene. | 0.870 |
HO | URA3 | YDL227C | YEL021W | Homothallic switching endonuclease; Site-specific endonuclease; required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p, and Ash1p. | Orotidine-5'-phosphate (OMP) decarboxylase; catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound. | 0.834 |
HO | YKU70 | YDL227C | YMR284W | Homothallic switching endonuclease; Site-specific endonuclease; required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p, and Ash1p. | ATP-dependent DNA helicase II subunit 1; Subunit of the telomeric Ku complex (Yku70p-Yku80p); involved in telomere length maintenance, structure and telomere position effect; required for localization of telomerase ribonucleoprotein to nucleus via interaction with the TLC1 guide RNA; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair. | 0.832 |
Q0255 | AI3 | Q0255 | Q0060 | Uncharacterized mitochondrial protein RF1; Maturase-like protein. | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceIII; encoded by a mobile group I intron within the mitochondrial COX1 gene. | 0.650 |
Q0255 | AI4 | Q0255 | Q0065 | Uncharacterized mitochondrial protein RF1; Maturase-like protein. | Truncated non-functional cytochrome oxidase 1; Endonuclease I-SceII; encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity. | 0.653 |
Q0255 | BI4 | Q0255 | Q0120 | Uncharacterized mitochondrial protein RF1; Maturase-like protein. | Truncated, nonfunctional cytochrome b; Mitochondrial mRNA maturase; forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA. | 0.935 |