node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALD2 | YML131W | YMR170C | YML131W | Cytoplasmic aldehyde dehydrogenase; involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p. | Uncharacterized membrane protein YML131W; Protein of unknown function; similar to medium chain dehydrogenase/reductases; expression induced by stresses including osmotic shock, DNA damaging agents, and other chemicals; GFP-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress. | 0.404 |
ALD2 | ZTA1 | YMR170C | YBR046C | Cytoplasmic aldehyde dehydrogenase; involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p. | Probable quinone oxidoreductase; NADPH-dependent quinone reductase; GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin. | 0.531 |
ALD4 | YML131W | YOR374W | YML131W | Mitochondrial aldehyde dehydrogenase; required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed; can substitute for cytosolic NADP-dependent aldehyde dehydrogenase when directed to the cytosol; human homolog ALDH2 can complement yeast ald4 mutant. | Uncharacterized membrane protein YML131W; Protein of unknown function; similar to medium chain dehydrogenase/reductases; expression induced by stresses including osmotic shock, DNA damaging agents, and other chemicals; GFP-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress. | 0.624 |
ALD4 | ZTA1 | YOR374W | YBR046C | Mitochondrial aldehyde dehydrogenase; required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed; can substitute for cytosolic NADP-dependent aldehyde dehydrogenase when directed to the cytosol; human homolog ALDH2 can complement yeast ald4 mutant. | Probable quinone oxidoreductase; NADPH-dependent quinone reductase; GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin. | 0.512 |
ENV9 | YML131W | YOR246C | YML131W | Probable oxidoreductase ENV9; Protein proposed to be involved in vacuolar functions; mutant shows defect in CPY processing and defects in vacuolar morphology; has similarity to oxidoreductases, found in lipid particles; required for replication of Brome mosaic virus in S. cerevisiae, a model system for studying replication of positive-strand RNA viruses in their natural hosts. | Uncharacterized membrane protein YML131W; Protein of unknown function; similar to medium chain dehydrogenase/reductases; expression induced by stresses including osmotic shock, DNA damaging agents, and other chemicals; GFP-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress. | 0.473 |
ENV9 | ZTA1 | YOR246C | YBR046C | Probable oxidoreductase ENV9; Protein proposed to be involved in vacuolar functions; mutant shows defect in CPY processing and defects in vacuolar morphology; has similarity to oxidoreductases, found in lipid particles; required for replication of Brome mosaic virus in S. cerevisiae, a model system for studying replication of positive-strand RNA viruses in their natural hosts. | Probable quinone oxidoreductase; NADPH-dependent quinone reductase; GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin. | 0.521 |
FMP23 | ZTA1 | YBR047W | YBR046C | Protein FMP23, mitochondrial; Putative protein of unknown function; proposed to be involved in iron or copper homeostasis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Probable quinone oxidoreductase; NADPH-dependent quinone reductase; GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin. | 0.591 |
YBL012C | YBL044W | YBL012C | YBL044W | Putative uncharacterized protein YBL012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative protein of unknown function; YBL044W is not an essential protein. | 0.837 |
YBL012C | YBL083C | YBL012C | YBL083C | Putative uncharacterized protein YBL012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Putative uncharacterized protein YBL083C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps verified ORF ALG3. | 0.830 |
YBL012C | YBR071W | YBL012C | YBR071W | Putative uncharacterized protein YBL012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Uncharacterized protein YBR071W; Protein of unknown function found in the cytoplasm and bud neck; mRNA expression may be regulated by the cell cycle and/or cell wall stress; overexpression of YBR071W affects endocytic protein trafficking. | 0.875 |
YBL012C | ZTA1 | YBL012C | YBR046C | Putative uncharacterized protein YBL012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | Probable quinone oxidoreductase; NADPH-dependent quinone reductase; GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin. | 0.637 |
YBL044W | YBL012C | YBL044W | YBL012C | Putative protein of unknown function; YBL044W is not an essential protein. | Putative uncharacterized protein YBL012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.837 |
YBL044W | YBL083C | YBL044W | YBL083C | Putative protein of unknown function; YBL044W is not an essential protein. | Putative uncharacterized protein YBL083C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps verified ORF ALG3. | 0.760 |
YBL044W | YBR071W | YBL044W | YBR071W | Putative protein of unknown function; YBL044W is not an essential protein. | Uncharacterized protein YBR071W; Protein of unknown function found in the cytoplasm and bud neck; mRNA expression may be regulated by the cell cycle and/or cell wall stress; overexpression of YBR071W affects endocytic protein trafficking. | 0.833 |
YBL044W | ZTA1 | YBL044W | YBR046C | Putative protein of unknown function; YBL044W is not an essential protein. | Probable quinone oxidoreductase; NADPH-dependent quinone reductase; GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin. | 0.557 |
YBL083C | YBL012C | YBL083C | YBL012C | Putative uncharacterized protein YBL083C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps verified ORF ALG3. | Putative uncharacterized protein YBL012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.830 |
YBL083C | YBL044W | YBL083C | YBL044W | Putative uncharacterized protein YBL083C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps verified ORF ALG3. | Putative protein of unknown function; YBL044W is not an essential protein. | 0.760 |
YBL083C | YBR071W | YBL083C | YBR071W | Putative uncharacterized protein YBL083C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps verified ORF ALG3. | Uncharacterized protein YBR071W; Protein of unknown function found in the cytoplasm and bud neck; mRNA expression may be regulated by the cell cycle and/or cell wall stress; overexpression of YBR071W affects endocytic protein trafficking. | 0.830 |
YBL083C | ZTA1 | YBL083C | YBR046C | Putative uncharacterized protein YBL083C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps verified ORF ALG3. | Probable quinone oxidoreductase; NADPH-dependent quinone reductase; GFP-tagged protein localizes to the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin. | 0.537 |
YBR071W | YBL012C | YBR071W | YBL012C | Uncharacterized protein YBR071W; Protein of unknown function found in the cytoplasm and bud neck; mRNA expression may be regulated by the cell cycle and/or cell wall stress; overexpression of YBR071W affects endocytic protein trafficking. | Putative uncharacterized protein YBL012C; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data. | 0.875 |