node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
KGD2 | YBR096W | YDR148C | YBR096W | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); Dihydrolipoyl transsuccinylase; component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated. | Uncharacterized protein YBR096W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER. | 0.493 |
LDH1 | SSP120 | YBR204C | YLR250W | Lipid droplet hydrolase 1; Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif). | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern. | 0.545 |
LDH1 | YBR096W | YBR204C | YBR096W | Lipid droplet hydrolase 1; Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif). | Uncharacterized protein YBR096W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER. | 0.452 |
LDH1 | YIM1 | YBR204C | YMR152W | Lipid droplet hydrolase 1; Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif). | Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; may have a role in lipid metabolism, based on localization to lipid droplets; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress. | 0.581 |
MON2 | YBR096W | YNL297C | YBR096W | Protein with a role in endocytosis and vacuole integrity; peripheral membrane protein; interacts with and negatively regulates Arl1p; localizes to the endosome; member of the Sec7p family of proteins. | Uncharacterized protein YBR096W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER. | 0.400 |
SSP120 | LDH1 | YLR250W | YBR204C | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern. | Lipid droplet hydrolase 1; Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif). | 0.545 |
SSP120 | YBR096W | YLR250W | YBR096W | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern. | Uncharacterized protein YBR096W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER. | 0.500 |
SSP120 | YIM1 | YLR250W | YMR152W | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern. | Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; may have a role in lipid metabolism, based on localization to lipid droplets; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress. | 0.536 |
YBR096W | KGD2 | YBR096W | YDR148C | Uncharacterized protein YBR096W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER. | 2-oxoglutarate dehydrogenase E2 component (dihydrolipoamide succinyltransferase); Dihydrolipoyl transsuccinylase; component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated. | 0.493 |
YBR096W | LDH1 | YBR096W | YBR204C | Uncharacterized protein YBR096W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER. | Lipid droplet hydrolase 1; Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif). | 0.452 |
YBR096W | MON2 | YBR096W | YNL297C | Uncharacterized protein YBR096W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER. | Protein with a role in endocytosis and vacuole integrity; peripheral membrane protein; interacts with and negatively regulates Arl1p; localizes to the endosome; member of the Sec7p family of proteins. | 0.400 |
YBR096W | SSP120 | YBR096W | YLR250W | Uncharacterized protein YBR096W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER. | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern. | 0.500 |
YBR096W | YIM1 | YBR096W | YMR152W | Uncharacterized protein YBR096W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER. | Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; may have a role in lipid metabolism, based on localization to lipid droplets; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress. | 0.443 |
YIM1 | LDH1 | YMR152W | YBR204C | Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; may have a role in lipid metabolism, based on localization to lipid droplets; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress. | Lipid droplet hydrolase 1; Serine hydrolase; exhibits active esterase plus weak triacylglycerol lipase activities; proposed role in lipid homeostasis, regulating phospholipid and non-polar lipid levels and required for mobilization of LD-stored lipids; localizes to the lipid droplet (LD) surface; contains a classical serine containing catalytic triad (GxSxG motif). | 0.581 |
YIM1 | SSP120 | YMR152W | YLR250W | Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; may have a role in lipid metabolism, based on localization to lipid droplets; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress. | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern. | 0.536 |
YIM1 | YBR096W | YMR152W | YBR096W | Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; may have a role in lipid metabolism, based on localization to lipid droplets; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress. | Uncharacterized protein YBR096W; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER. | 0.443 |