node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LUC7 | MUD1 | YDL087C | YBR119W | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | 0.999 |
LUC7 | NAM8 | YDL087C | YHR086W | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of REC107 pre-mRNA; Nam8p regulon embraces the meiotic pre-mRNAs of REC107, HFM1, AMA1 SPO22 and PCH2; the putative RNA binding domains RRM2 and RRM3 are required for Nam8p meiotic function. | 0.999 |
LUC7 | PRP40 | YDL087C | YKL012W | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | Pre-mRNA-processing protein PRP40; U1 snRNP protein involved in splicing; interacts with the branchpoint-binding protein during the formation of the second commitment complex. | 0.999 |
LUC7 | PRP42 | YDL087C | YDR235W | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | U1 small nuclear ribonucleoprotein component PRP42; U1 snRNP protein involved in splicing; required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats. | 0.999 |
LUC7 | PRP9 | YDL087C | YDL030W | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | Pre-mRNA-splicing factor PRP9; Subunit of the SF3a splicing factor complex; required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex; Belongs to the SF3A3 family. | 0.983 |
LUC7 | SMD1 | YDL087C | YGR074W | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | Small nuclear ribonucleoprotein Sm D1; Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; relocalizes to the cytosol in response to hypoxia; homolog of human Sm D1; protein abundance increases in response to DNA replication stress. | 0.999 |
LUC7 | SMX2 | YDL087C | YFL017W-A | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | Small nuclear ribonucleoprotein G; Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G. | 0.997 |
LUC7 | SNP1 | YDL087C | YIL061C | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | U1 small nuclear ribonucleoprotein 70 kDa homolog; Component of U1 snRNP required for mRNA splicing via spliceosome; substrate of the arginine methyltransferase Hmt1p; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein; protein abundance increases in response to DNA replication stress. | 0.999 |
LUC7 | SNU56 | YDL087C | YDR240C | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | 56 kDa U1 small nuclear ribonucleoprotein component; Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; interacts with mRNA in commitment complex. | 0.999 |
LUC7 | SNU71 | YDL087C | YGR013W | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | U1 small nuclear ribonucleoprotein component SNU71; Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; Belongs to the SNU71 family. | 0.999 |
MUD1 | LUC7 | YBR119W | YDL087C | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA; relocalizes to the cytosol in response to hypoxia; Belongs to the Luc7 family. | 0.999 |
MUD1 | NAM8 | YBR119W | YHR086W | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of REC107 pre-mRNA; Nam8p regulon embraces the meiotic pre-mRNAs of REC107, HFM1, AMA1 SPO22 and PCH2; the putative RNA binding domains RRM2 and RRM3 are required for Nam8p meiotic function. | 0.999 |
MUD1 | PRP40 | YBR119W | YKL012W | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | Pre-mRNA-processing protein PRP40; U1 snRNP protein involved in splicing; interacts with the branchpoint-binding protein during the formation of the second commitment complex. | 0.999 |
MUD1 | PRP42 | YBR119W | YDR235W | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | U1 small nuclear ribonucleoprotein component PRP42; U1 snRNP protein involved in splicing; required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats. | 0.999 |
MUD1 | PRP9 | YBR119W | YDL030W | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | Pre-mRNA-splicing factor PRP9; Subunit of the SF3a splicing factor complex; required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex; Belongs to the SF3A3 family. | 0.999 |
MUD1 | SMD1 | YBR119W | YGR074W | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | Small nuclear ribonucleoprotein Sm D1; Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; relocalizes to the cytosol in response to hypoxia; homolog of human Sm D1; protein abundance increases in response to DNA replication stress. | 0.999 |
MUD1 | SMX2 | YBR119W | YFL017W-A | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | Small nuclear ribonucleoprotein G; Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G. | 0.999 |
MUD1 | SNP1 | YBR119W | YIL061C | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | U1 small nuclear ribonucleoprotein 70 kDa homolog; Component of U1 snRNP required for mRNA splicing via spliceosome; substrate of the arginine methyltransferase Hmt1p; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein; protein abundance increases in response to DNA replication stress. | 0.999 |
MUD1 | SNU56 | YBR119W | YDR240C | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | 56 kDa U1 small nuclear ribonucleoprotein component; Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; interacts with mRNA in commitment complex. | 0.999 |
MUD1 | SNU71 | YBR119W | YGR013W | U1 snRNP A protein; homolog of human U1-A; involved in nuclear mRNA splicing; Belongs to the RRM U1 A/B'' family. | U1 small nuclear ribonucleoprotein component SNU71; Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; Belongs to the SNU71 family. | 0.999 |