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FRM2 protein (Saccharomyces cerevisiae) - STRING interaction network
"FRM2" - Protein of unknown function, involved in the integration of lipid signaling pathways with cellular homeostasis in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
FRM2Protein of unknown function, involved in the integration of lipid signaling pathways with cellular homeostasis; expression induced in cells treated with the mycotoxin patulin; has similarity to bacterial nitroreductases; Involved in negative regulation of fatty acid metabolism (193 aa)    
Predicted Functional Partners:
YCR102C
Putative protein of unknown function, involved in copper metabolism; similar to C. carbonum toxD gene; member of the quinone oxidoreductase family (368 aa)
     
   
  0.554
YLL056C
Putative protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p and genes involved in pleiotropic drug resistance (PDR); expression is induced in cells treated with the mycotoxin patulin (298 aa)
     
   
  0.551
YCR049C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data (148 aa)
           
  0.544
YCR041W
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; May play a role in proper chromosome segregation. Suppresses the high-frequency loss of mini-chromosomes when overexpressed, and this suppression is completely dependent on silencing protein SIR4 (110 aa)
           
  0.543
FLR1
Plasma membrane multidrug transporter of the major facilitator superfamily, involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs; expression induced in cells treated with the mycotoxin patulin; Probable efflux transporter. Confers resistance to the azole derivative fluconazole (FCZ) (548 aa)
     
   
  0.497
SNG1
Protein involved in resistance to nitrosoguanidine (MNNG) and 6-azauracil (6-AU); expression is regulated by transcription factors involved in multidrug resistance; May function as a N-methyl-N’nitro-N-nitrosoguanidine (MNNG) export permease (547 aa)
           
  0.482
YCR6C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data (157 aa)
           
  0.448
GTT2
Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p (233 aa)
     
   
  0.427
YCR25C
Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data; YCR025C is not an essential gene (136 aa)
           
  0.412
YCR043C
Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi apparatus; YCR043C is not an essential gene (127 aa)
           
  0.412
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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