node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ARE1 | YCR099C | YCR048W | YCR099C | Sterol O-acyltransferase 1; Acyl-CoA:sterol acyltransferase; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen; ARE1 has a paralog, ARE2, that arose from the whole genome duplication. | Uncharacterized protein YCR099C; Putative protein of unknown function. | 0.605 |
CWH43 | YCP4 | YCR017C | YCR004C | Protein CWH43; GPI lipid remodelase; responsible for introducing ceramides into GPI anchors having a C26:0 fatty acid in sn-2 of the glycerol moiety; can also use lyso-GPI protein anchors and various base resistant lipids as substrates; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion; In the C-terminal section; belongs to the PGAP2IP family. | Flavoprotein-like protein YCP4; Protein of unknown function; has sequence and structural similarity to flavodoxins; predicted to be palmitoylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.538 |
CWH43 | YCR099C | YCR017C | YCR099C | Protein CWH43; GPI lipid remodelase; responsible for introducing ceramides into GPI anchors having a C26:0 fatty acid in sn-2 of the glycerol moiety; can also use lyso-GPI protein anchors and various base resistant lipids as substrates; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion; In the C-terminal section; belongs to the PGAP2IP family. | Uncharacterized protein YCR099C; Putative protein of unknown function. | 0.744 |
CYS3 | YCR099C | YAL012W | YCR099C | Cystathionine gamma-lyase; catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine; protein abundance increases in response to DNA replication stress; Belongs to the trans-sulfuration enzymes family. | Uncharacterized protein YCR099C; Putative protein of unknown function. | 0.410 |
GEP3 | YCR099C | YOR205C | YCR099C | Genetic interactor of prohibitins 3, mitochondrial; Protein required for mitochondrial ribosome small subunit biogenesis; null mutant is defective in respiration and in maturation of 15S rRNA; protein is localized to the mitochondrial inner membrane; null mutant interacts synthetically with prohibitin (Phb1p); Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily. | Uncharacterized protein YCR099C; Putative protein of unknown function. | 0.447 |
PEX34 | YCR099C | YCL056C | YCR099C | Protein that regulates peroxisome populations; peroxisomal integral membrane protein; interacts with Pex11p, Pex25p, and Pex27p to control both constitutive peroxisome division and peroxisome morphology and abundance during peroxisome proliferation. | Uncharacterized protein YCR099C; Putative protein of unknown function. | 0.695 |
SEC13 | YCR099C | YLR208W | YCR099C | Protein transport protein SEC13; Structural component of 3 complexes; subunit of the Nup84p nuclear pore subcomplex that contributes to nucleocytoplasmic transport and NPC biogenesis; subunit of the COPII vesicle coat required for ER-to-Golgi transport; subunit of SEACAT, a subcomplex of the coatomer-related, vacuolar-associated SEA complex, that inhibits the TORC1 inhibitory role of SEACIT (Iml1p-Npr2p-Npr3p), a GAP for Gtr1p, thereby resulting in activation of TORC1 signaling; human SEC13 homolog. | Uncharacterized protein YCR099C; Putative protein of unknown function. | 0.497 |
YBL059W | YCR099C | YBL059W | YCR099C | Uncharacterized protein YBL059W; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YBL059W has a paralog, YER093C-A, that arose from the whole genome duplication. | Uncharacterized protein YCR099C; Putative protein of unknown function. | 0.600 |
YCP4 | CWH43 | YCR004C | YCR017C | Flavoprotein-like protein YCP4; Protein of unknown function; has sequence and structural similarity to flavodoxins; predicted to be palmitoylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Protein CWH43; GPI lipid remodelase; responsible for introducing ceramides into GPI anchors having a C26:0 fatty acid in sn-2 of the glycerol moiety; can also use lyso-GPI protein anchors and various base resistant lipids as substrates; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion; In the C-terminal section; belongs to the PGAP2IP family. | 0.538 |
YCP4 | YCR099C | YCR004C | YCR099C | Flavoprotein-like protein YCP4; Protein of unknown function; has sequence and structural similarity to flavodoxins; predicted to be palmitoylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Uncharacterized protein YCR099C; Putative protein of unknown function. | 0.693 |
YCR099C | ARE1 | YCR099C | YCR048W | Uncharacterized protein YCR099C; Putative protein of unknown function. | Sterol O-acyltransferase 1; Acyl-CoA:sterol acyltransferase; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen; ARE1 has a paralog, ARE2, that arose from the whole genome duplication. | 0.605 |
YCR099C | CWH43 | YCR099C | YCR017C | Uncharacterized protein YCR099C; Putative protein of unknown function. | Protein CWH43; GPI lipid remodelase; responsible for introducing ceramides into GPI anchors having a C26:0 fatty acid in sn-2 of the glycerol moiety; can also use lyso-GPI protein anchors and various base resistant lipids as substrates; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion; In the C-terminal section; belongs to the PGAP2IP family. | 0.744 |
YCR099C | CYS3 | YCR099C | YAL012W | Uncharacterized protein YCR099C; Putative protein of unknown function. | Cystathionine gamma-lyase; catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine; protein abundance increases in response to DNA replication stress; Belongs to the trans-sulfuration enzymes family. | 0.410 |
YCR099C | GEP3 | YCR099C | YOR205C | Uncharacterized protein YCR099C; Putative protein of unknown function. | Genetic interactor of prohibitins 3, mitochondrial; Protein required for mitochondrial ribosome small subunit biogenesis; null mutant is defective in respiration and in maturation of 15S rRNA; protein is localized to the mitochondrial inner membrane; null mutant interacts synthetically with prohibitin (Phb1p); Belongs to the TRAFAC class YlqF/YawG GTPase family. GEP3 subfamily. | 0.447 |
YCR099C | PEX34 | YCR099C | YCL056C | Uncharacterized protein YCR099C; Putative protein of unknown function. | Protein that regulates peroxisome populations; peroxisomal integral membrane protein; interacts with Pex11p, Pex25p, and Pex27p to control both constitutive peroxisome division and peroxisome morphology and abundance during peroxisome proliferation. | 0.695 |
YCR099C | SEC13 | YCR099C | YLR208W | Uncharacterized protein YCR099C; Putative protein of unknown function. | Protein transport protein SEC13; Structural component of 3 complexes; subunit of the Nup84p nuclear pore subcomplex that contributes to nucleocytoplasmic transport and NPC biogenesis; subunit of the COPII vesicle coat required for ER-to-Golgi transport; subunit of SEACAT, a subcomplex of the coatomer-related, vacuolar-associated SEA complex, that inhibits the TORC1 inhibitory role of SEACIT (Iml1p-Npr2p-Npr3p), a GAP for Gtr1p, thereby resulting in activation of TORC1 signaling; human SEC13 homolog. | 0.497 |
YCR099C | YBL059W | YCR099C | YBL059W | Uncharacterized protein YCR099C; Putative protein of unknown function. | Uncharacterized protein YBL059W; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YBL059W has a paralog, YER093C-A, that arose from the whole genome duplication. | 0.600 |
YCR099C | YCP4 | YCR099C | YCR004C | Uncharacterized protein YCR099C; Putative protein of unknown function. | Flavoprotein-like protein YCP4; Protein of unknown function; has sequence and structural similarity to flavodoxins; predicted to be palmitoylated; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.693 |
YCR099C | YCR100C | YCR099C | YCR100C | Uncharacterized protein YCR099C; Putative protein of unknown function. | Uncharacterized protein YCR100C; Putative protein of unknown function. | 0.881 |
YCR100C | YCR099C | YCR100C | YCR099C | Uncharacterized protein YCR100C; Putative protein of unknown function. | Uncharacterized protein YCR099C; Putative protein of unknown function. | 0.881 |