node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAD4 | PAU3 | YDL243C | YCR104W | Putative aryl-alcohol dehydrogenase; involved in oxidative stress response; similar to P. chrysosporium aryl-alcohol dehydrogenase; expression induced in cells treated with the mycotoxin patulin; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family. | Seripauperin-3; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. | 0.463 |
AAD4 | YCR102C | YDL243C | YCR102C | Putative aryl-alcohol dehydrogenase; involved in oxidative stress response; similar to P. chrysosporium aryl-alcohol dehydrogenase; expression induced in cells treated with the mycotoxin patulin; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family. | Uncharacterized protein YCR102C; Putative protein of unknown function; involved in copper metabolism; similar to C. carbonum toxD gene; member of the quinone oxidoreductase family; Belongs to the YCR102c/YLR460c/YNL134c family. | 0.674 |
AAD4 | YKL070W | YDL243C | YKL070W | Putative aryl-alcohol dehydrogenase; involved in oxidative stress response; similar to P. chrysosporium aryl-alcohol dehydrogenase; expression induced in cells treated with the mycotoxin patulin; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family. | Uncharacterized protein YKL070W; Putative protein of unknown function; expression induced in cells treated with mycotoxins patulin or citrinin; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.668 |
AQY2 | YCR102C | YLL052C | YCR102C | Aquaporin-like protein 2; Water channel that mediates water transport across cell membranes; only expressed in proliferating cells; controlled by osmotic signals; may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Uncharacterized protein YCR102C; Putative protein of unknown function; involved in copper metabolism; similar to C. carbonum toxD gene; member of the quinone oxidoreductase family; Belongs to the YCR102c/YLR460c/YNL134c family. | 0.513 |
AQY2 | YLR460C | YLL052C | YLR460C | Aquaporin-like protein 2; Water channel that mediates water transport across cell membranes; only expressed in proliferating cells; controlled by osmotic signals; may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains; Belongs to the MIP/aquaporin (TC 1.A.8) family. | Uncharacterized protein YLR460C; Member of the quinone oxidoreductase family; up-regulated in response to the fungicide mancozeb; possibly up-regulated by iodine. | 0.496 |
AST1 | YCR102C | YBL069W | YCR102C | Protein AST1; Lipid raft associated protein; interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane by influencing its incorporation into lipid rafts; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST1 has a paralog, AST2, that arose from the whole genome duplication. | Uncharacterized protein YCR102C; Putative protein of unknown function; involved in copper metabolism; similar to C. carbonum toxD gene; member of the quinone oxidoreductase family; Belongs to the YCR102c/YLR460c/YNL134c family. | 0.563 |
AST1 | YLR460C | YBL069W | YLR460C | Protein AST1; Lipid raft associated protein; interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane by influencing its incorporation into lipid rafts; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST1 has a paralog, AST2, that arose from the whole genome duplication. | Uncharacterized protein YLR460C; Member of the quinone oxidoreductase family; up-regulated in response to the fungicide mancozeb; possibly up-regulated by iodine. | 0.568 |
AST2 | YCR102C | YER101C | YCR102C | Protein AST2; Lipid raft associated protein; overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST2 has a paralog, AST1, that arose from the whole genome duplication. | Uncharacterized protein YCR102C; Putative protein of unknown function; involved in copper metabolism; similar to C. carbonum toxD gene; member of the quinone oxidoreductase family; Belongs to the YCR102c/YLR460c/YNL134c family. | 0.530 |
AST2 | YLR460C | YER101C | YLR460C | Protein AST2; Lipid raft associated protein; overexpression restores Pma1p localization to lipid rafts which is required for targeting of Pma1p to the plasma membrane; sometimes classified in the medium-chain dehydrogenase/reductases (MDRs) superfamily; AST2 has a paralog, AST1, that arose from the whole genome duplication. | Uncharacterized protein YLR460C; Member of the quinone oxidoreductase family; up-regulated in response to the fungicide mancozeb; possibly up-regulated by iodine. | 0.518 |
PAU14 | PAU3 | YIL176C | YCR104W | Seripauperin-14; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; identical to Pau1p; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. | Seripauperin-3; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. | 0.891 |
PAU14 | PAU8 | YIL176C | YAL068C | Seripauperin-14; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; identical to Pau1p; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. | Seripauperin-11; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. | 0.873 |
PAU14 | YCR102C | YIL176C | YCR102C | Seripauperin-14; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; identical to Pau1p; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. | Uncharacterized protein YCR102C; Putative protein of unknown function; involved in copper metabolism; similar to C. carbonum toxD gene; member of the quinone oxidoreductase family; Belongs to the YCR102c/YLR460c/YNL134c family. | 0.647 |
PAU14 | YML083C | YIL176C | YML083C | Seripauperin-14; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; identical to Pau1p; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. | Putative uncharacterized protein YML083C; Protein of unknown function; transcriptionally regulated by Upc2p via an upstream sterol response element; strong increase in transcript abundance during anaerobic growth compared to aerobic growth; cells deleted for YML083C do not exhibit growth defects in anerobic or anaerobic conditions. | 0.582 |
PAU3 | AAD4 | YCR104W | YDL243C | Seripauperin-3; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. | Putative aryl-alcohol dehydrogenase; involved in oxidative stress response; similar to P. chrysosporium aryl-alcohol dehydrogenase; expression induced in cells treated with the mycotoxin patulin; members of the AAD gene family comprise three pairs (AAD3 + AAD15, AAD6/AAD16 + AAD4, AAD10 + AAD14) whose two genes are more related to one another than to other members of the family. | 0.463 |
PAU3 | PAU14 | YCR104W | YIL176C | Seripauperin-3; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. | Seripauperin-14; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; identical to Pau1p; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. | 0.891 |
PAU3 | PAU8 | YCR104W | YAL068C | Seripauperin-3; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. | Seripauperin-11; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. | 0.816 |
PAU3 | YCR102C | YCR104W | YCR102C | Seripauperin-3; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. | Uncharacterized protein YCR102C; Putative protein of unknown function; involved in copper metabolism; similar to C. carbonum toxD gene; member of the quinone oxidoreductase family; Belongs to the YCR102c/YLR460c/YNL134c family. | 0.630 |
PAU3 | YML083C | YCR104W | YML083C | Seripauperin-3; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. | Putative uncharacterized protein YML083C; Protein of unknown function; transcriptionally regulated by Upc2p via an upstream sterol response element; strong increase in transcript abundance during anaerobic growth compared to aerobic growth; cells deleted for YML083C do not exhibit growth defects in anerobic or anaerobic conditions. | 0.470 |
PAU8 | PAU14 | YAL068C | YIL176C | Seripauperin-11; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. | Seripauperin-14; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; identical to Pau1p; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. | 0.873 |
PAU8 | PAU3 | YAL068C | YCR104W | Seripauperin-11; Protein of unknown function; member of the seripauperin multigene family encoded mainly in subtelomeric regions; Belongs to the SRP1/TIP1 family. Seripauperin subfamily. | Seripauperin-3; Member of the seripauperin multigene family; encoded mainly in subtelomeric region; active during alcoholic fermentation; regulated by anaerobiosis; negatively regulated by oxygen; repressed by heme. | 0.816 |