node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PRE1 | PRE10 | YER012W | YOR362C | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | 0.999 |
PRE1 | PRE3 | YER012W | YJL001W | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | Beta 1 subunit of the 20S proteasome; responsible for cleavage after acidic residues in peptides. | 0.999 |
PRE1 | PRE4 | YER012W | YFR050C | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | Beta 7 subunit of the 20S proteasome; Belongs to the peptidase T1B family. | 0.999 |
PRE1 | PRE7 | YER012W | YBL041W | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | Beta 6 subunit of the 20S proteasome. | 0.999 |
PRE1 | PRE8 | YER012W | YML092C | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | Alpha 2 subunit of the 20S proteasome; Belongs to the peptidase T1A family. | 0.999 |
PRE1 | PRE9 | YER012W | YGR135W | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | Alpha 3 subunit of the 20S proteasome; the only nonessential 20S subunit; may be replaced by the alpha 4 subunit (Pre6p) under stress conditions to create a more active proteasomal isoform; Belongs to the peptidase T1A family. | 0.999 |
PRE1 | PUP2 | YER012W | YGR253C | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | Alpha 5 subunit of the 20S proteasome; involved in ubiquitin-dependent catabolism; human homolog is subunit zeta; Belongs to the peptidase T1A family. | 0.999 |
PRE1 | PUP3 | YER012W | YER094C | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | Beta 3 subunit of the 20S proteasome; involved in ubiquitin-dependent catabolism; human homolog is subunit C10. | 0.999 |
PRE1 | RPT2 | YER012W | YDL007W | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle; N-myristoylation of Rpt2p at Gly2 is involved in regulating the proper intracellular distribution of proteasome activity by controlling the nuclear localization of the 26S proteasome. | 0.999 |
PRE1 | YDR182W-A | YER012W | YDR182W-A | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | Uncharacterized protein YDR182W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.979 |
PRE10 | PRE1 | YOR362C | YER012W | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle; Belongs to the peptidase T1B family. | 0.999 |
PRE10 | PRE3 | YOR362C | YJL001W | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | Beta 1 subunit of the 20S proteasome; responsible for cleavage after acidic residues in peptides. | 0.999 |
PRE10 | PRE4 | YOR362C | YFR050C | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | Beta 7 subunit of the 20S proteasome; Belongs to the peptidase T1B family. | 0.999 |
PRE10 | PRE7 | YOR362C | YBL041W | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | Beta 6 subunit of the 20S proteasome. | 0.999 |
PRE10 | PRE8 | YOR362C | YML092C | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | Alpha 2 subunit of the 20S proteasome; Belongs to the peptidase T1A family. | 0.999 |
PRE10 | PRE9 | YOR362C | YGR135W | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | Alpha 3 subunit of the 20S proteasome; the only nonessential 20S subunit; may be replaced by the alpha 4 subunit (Pre6p) under stress conditions to create a more active proteasomal isoform; Belongs to the peptidase T1A family. | 0.999 |
PRE10 | PUP2 | YOR362C | YGR253C | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | Alpha 5 subunit of the 20S proteasome; involved in ubiquitin-dependent catabolism; human homolog is subunit zeta; Belongs to the peptidase T1A family. | 0.999 |
PRE10 | PUP3 | YOR362C | YER094C | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | Beta 3 subunit of the 20S proteasome; involved in ubiquitin-dependent catabolism; human homolog is subunit C10. | 0.999 |
PRE10 | RPT2 | YOR362C | YDL007W | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | ATPase of the 19S regulatory particle of the 26S proteasome; one of six ATPases of the regulatory particle; involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle; N-myristoylation of Rpt2p at Gly2 is involved in regulating the proper intracellular distribution of proteasome activity by controlling the nuclear localization of the 26S proteasome. | 0.999 |
PRE10 | YDR182W-A | YOR362C | YDR182W-A | Alpha 7 subunit of the 20S proteasome; protein abundance increases in response to DNA replication stress. | Uncharacterized protein YDR182W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.973 |