STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YHR050W-APutative uncharacterized protein YHR050W-A; Protein of unknown function; identified by expression profiling and mass spectrometry. (56 aa)    
Predicted Functional Partners:
PMP3
Small plasma membrane protein; confers resistance to amphotericin B and is a potential target of this common antifungal drug; related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature; not essential for viability; deletion causes hyperpolarization of the plasma membrane potential; Belongs to the UPF0057 (PMP3) family.
   
   0.464
YBL039W-B
Uncharacterized protein YBL039W-B; Putative protein of unknown function; mCherry fusion protein localizes to the vacuole.
   
    0.447
YJL127C-B
UPF0618 protein YJL127C-B; Putative protein of unknown function; identified based on homology to the filamentous fungus, <i>Ashbya gossypii</i>; SWAT-GFP and seamless-GFP fusion proteins localize to the mitochondria.
   
    0.447
NCE101
Non-classical export protein 1; Protein of unknown function; involved in secretion of proteins that lack classical secretory signal sequences; SWAT-GFP and mCherry fusion proteins localize to the cytosol; Belongs to the NCE101 family.
   
    0.447
YBR126W-B
Putative uncharacterized protein YBR126W-B; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF YBR126W-A; identified by SAGE.
   
    0.445
COX9
Subunit VIIa of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain.
   
    0.445
YDR003W-A
Uncharacterized protein YDR003W-A; Putative protein of unknown function; identified by expression profiling and mass spectrometry.
   
    0.445
YJL127W-A
Putative uncharacterized protein YJL127W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data.
   
    0.445
YOR376W-A
Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR.
   
    0.445
YER175W-A
Uncharacterized protein YER175W-A; Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching.
   
    0.444
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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