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LOH1 protein (Saccharomyces cerevisiae) - STRING interaction network
"LOH1" - Protein of unknown function with proposed roles in maintenance of genome integrity and also in spore wall assembly in Saccharomyces cerevisiae
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
LOH1Protein of unknown function with proposed roles in maintenance of genome integrity and also in spore wall assembly; induced during sporulation; repressed during vegetative growth by Sum1p and Hst1p; sequence similar to IRC1; Involved in spore wall assembly (PubMed-23966878). May be involved in maintaining genome integrity (PubMed-18562670) (219 aa)    
Predicted Functional Partners:
LDS1
Putative protein of unknown function; Involved in spore wall assembly (325 aa)
     
   
  0.663
CDA1
Chitin deacetylase, together with Cda2p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall; Hydrolyzes the N-acetamido groups of N-acetyl-D- glucosamine residues in chitin (301 aa)
     
   
  0.555
YGL230C
Putative protein of unknown function; non-essential gene (147 aa)
     
   
  0.550
PES4
Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation, similar to Mip6p (611 aa)
     
   
  0.481
YFL012W
Putative protein of unknown function; transcribed during sporulation; null mutant exhibits increased resistance to rapamycin (148 aa)
     
   
  0.477
MIP6
Putative RNA-binding protein, interacts with Mex67p, which is a component of the nuclear pore involved in nuclear mRNA export (659 aa)
     
   
  0.450
GAS4
1,3-beta-glucanosyltransferase, involved with Gas2p in spore wall assembly; has similarity to Gas1p; localizes to the cell wall; Splits internally a 1,3-beta-glucan molecule and transfers the newly generated reducing end (the donor) to the non- reducing end of another 1,3-beta-glucan molecule (the acceptor) forming a 1,3-beta linkage, resulting in the elongation of 1,3- beta-glucan chains in the cell wall. Involved in spore wall assembly (471 aa)
     
   
  0.425
YGL138C
Putative protein of unknown function; has no significant sequence similarity to any known protein (345 aa)
           
  0.418
RFM1
DNA-binding protein required for vegetative repression of middle sporulation genes; specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p; involved in telomere maintenance; Tethering factor required for histone deacetylase HST1- mediated repression. Probably involved in targeting HST1 to a subset of SUM1-regulated genes (310 aa)
           
  0.418
SHE10
Putative glycosylphosphatidylinositol (GPI)-anchored protein of unknown function; overexpression causes growth arrest; Involved in spore wall assembly (PubMed-23966878). May be a component of the mitochondrial RNase MRP (MtMRP), a ribonucleoprotein endoribonuclease involved in the cleaving RNA transcripts to generate primers for DNA replication in mitochondria (PubMed-20086051). Causes growth arrest when highly overexpressed (PubMed-7762298) (577 aa)
           
  0.416
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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