node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BSC6 | YJL163C | YOL137W | YJL163C | Bypass of stop codon protein 6; Protein of unknown function with 8 putative transmembrane segments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression. | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | 0.662 |
BSC6 | YMR155W | YOL137W | YMR155W | Bypass of stop codon protein 6; Protein of unknown function with 8 putative transmembrane segments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression. | Uncharacterized membrane protein YMR155W; Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen. | 0.421 |
DCS2 | GLC3 | YOR173W | YEL011W | Inactive diphosphatase DCS2; m(7)GpppX pyrophosphatase regulator; non-essential, stress induced regulatory protein; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway; mutant has increased aneuploidy tolerance; DCS2 has a paralog, DCS1, that arose from the whole genome duplication; Belongs to the HIT family. | Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; glycogen accumulation defect of the null mutant is functionally complemented by human GBE1, which is associated with glycogen storage disease; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | 0.799 |
DCS2 | YJL163C | YOR173W | YJL163C | Inactive diphosphatase DCS2; m(7)GpppX pyrophosphatase regulator; non-essential, stress induced regulatory protein; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway; mutant has increased aneuploidy tolerance; DCS2 has a paralog, DCS1, that arose from the whole genome duplication; Belongs to the HIT family. | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | 0.444 |
DCS2 | YLR149C | YOR173W | YLR149C | Inactive diphosphatase DCS2; m(7)GpppX pyrophosphatase regulator; non-essential, stress induced regulatory protein; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway; mutant has increased aneuploidy tolerance; DCS2 has a paralog, DCS1, that arose from the whole genome duplication; Belongs to the HIT family. | Uncharacterized protein YLR149C; Protein of unknown function; overexpression causes a cell cycle delay or arrest; null mutation results in a decrease in plasma membrane electron transport; YLR149C is not an essential gene; protein abundance increases in response to DNA replication stress. | 0.674 |
FMP42 | YJL163C | YMR221C | YJL163C | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; physical interaction with Atg27p suggests a possible role in autophagy. | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | 0.442 |
GLC3 | DCS2 | YEL011W | YOR173W | Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; glycogen accumulation defect of the null mutant is functionally complemented by human GBE1, which is associated with glycogen storage disease; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | Inactive diphosphatase DCS2; m(7)GpppX pyrophosphatase regulator; non-essential, stress induced regulatory protein; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway; mutant has increased aneuploidy tolerance; DCS2 has a paralog, DCS1, that arose from the whole genome duplication; Belongs to the HIT family. | 0.799 |
GLC3 | YJL163C | YEL011W | YJL163C | Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; glycogen accumulation defect of the null mutant is functionally complemented by human GBE1, which is associated with glycogen storage disease; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | 0.448 |
GLC3 | YLR149C | YEL011W | YLR149C | Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; relocalizes from nucleus to cytoplasmic foci upon DNA replication stress; glycogen accumulation defect of the null mutant is functionally complemented by human GBE1, which is associated with glycogen storage disease; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. | Uncharacterized protein YLR149C; Protein of unknown function; overexpression causes a cell cycle delay or arrest; null mutation results in a decrease in plasma membrane electron transport; YLR149C is not an essential gene; protein abundance increases in response to DNA replication stress. | 0.614 |
RRT8 | YJL163C | YOL048C | YJL163C | Protein involved in spore wall assembly; shares similarity with Lds1p and Lds2p and a strain mutant for all 3 genes exhibits reduced dityrosine fluorescence relative to the single mutants; identified in a screen for mutants with increased levels of rDNA transcription; green fluorescent protein (GFP)-fusion protein localizes to lipid particles; protein abundance increases in response to DNA replication stress. | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | 0.469 |
VBA1 | VBA2 | YMR088C | YBR293W | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | 0.482 |
VBA1 | YJL163C | YMR088C | YJL163C | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | 0.763 |
VBA1 | YMR155W | YMR088C | YMR155W | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Uncharacterized membrane protein YMR155W; Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen. | 0.585 |
VBA2 | VBA1 | YBR293W | YMR088C | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | 0.482 |
VBA2 | YJL163C | YBR293W | YJL163C | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | 0.791 |
VBA2 | YMR155W | YBR293W | YMR155W | Permease of basic amino acids in the vacuolar membrane; Belongs to the major facilitator superfamily. | Uncharacterized membrane protein YMR155W; Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen. | 0.616 |
YFL040W | YJL163C | YFL040W | YJL163C | Probable metabolite transport protein YFL040W; Putative transporter; member of the sugar porter family; YFL040W is not an essential gene; may have a role in intracellular sterol transport. | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | 0.460 |
YJL163C | BSC6 | YJL163C | YOL137W | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | Bypass of stop codon protein 6; Protein of unknown function with 8 putative transmembrane segments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression. | 0.662 |
YJL163C | DCS2 | YJL163C | YOR173W | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | Inactive diphosphatase DCS2; m(7)GpppX pyrophosphatase regulator; non-essential, stress induced regulatory protein; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway; mutant has increased aneuploidy tolerance; DCS2 has a paralog, DCS1, that arose from the whole genome duplication; Belongs to the HIT family. | 0.444 |
YJL163C | FMP42 | YJL163C | YMR221C | Uncharacterized membrane protein YJL163C; Putative protein of unknown function. | Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; physical interaction with Atg27p suggests a possible role in autophagy. | 0.442 |