node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CCW14 | CIS3 | YLR390W-A | YJL158C | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | 0.638 |
CCW14 | CRH1 | YLR390W-A | YGR189C | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Probable glycosidase CRH1; Chitin transglycosylase; functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress. | 0.677 |
CCW14 | CWP1 | YLR390W-A | YKL096W | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Cell wall mannoprotein that localizes to birth scars of daughter cells; linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; required for propionic acid resistance; Belongs to the SRP1/TIP1 family. | 0.766 |
CCW14 | NCW2 | YLR390W-A | YLR194C | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Cell wall biogenesis protein NCW2; Structural constituent of the cell wall; attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress; null mutant is sensitive to the antifungal agent polyhexamethylene biguanide, resistant to zymolyase treatment and has increased chitin deposition. | 0.543 |
CCW14 | PIR3 | YLR390W-A | YKL163W | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | O-glycosylated covalently-bound cell wall protein; required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway; coding sequence contains length polymorphisms in different strains; PIR3 has a paralog, HSP150, that arose from the whole genome duplication. | 0.632 |
CCW14 | PST1 | YLR390W-A | YDR055W | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1; PST1 has a paralog, ECM33, that arose from the whole genome duplication; Belongs to the SPS2 family. | 0.742 |
CCW14 | RLM1 | YLR390W-A | YPL089C | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | MADS-box transcription factor; component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p; RLM1 has a paralog, SMP1, that arose from the whole genome duplication. | 0.422 |
CCW14 | SED1 | YLR390W-A | YDR077W | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Cell wall protein SED1; Major stress-induced structural GPI-cell wall glycoprotein; associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites; SED1 has a paralog, SPI1, that arose from the whole genome duplication. | 0.695 |
CIS3 | CCW14 | YJL158C | YLR390W-A | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | 0.638 |
CIS3 | CRH1 | YJL158C | YGR189C | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Probable glycosidase CRH1; Chitin transglycosylase; functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress. | 0.697 |
CIS3 | CWP1 | YJL158C | YKL096W | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Cell wall mannoprotein that localizes to birth scars of daughter cells; linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; required for propionic acid resistance; Belongs to the SRP1/TIP1 family. | 0.541 |
CIS3 | PIR3 | YJL158C | YKL163W | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | O-glycosylated covalently-bound cell wall protein; required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway; coding sequence contains length polymorphisms in different strains; PIR3 has a paralog, HSP150, that arose from the whole genome duplication. | 0.789 |
CIS3 | PST1 | YJL158C | YDR055W | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1; PST1 has a paralog, ECM33, that arose from the whole genome duplication; Belongs to the SPS2 family. | 0.503 |
CIS3 | SED1 | YJL158C | YDR077W | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | Cell wall protein SED1; Major stress-induced structural GPI-cell wall glycoprotein; associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites; SED1 has a paralog, SPI1, that arose from the whole genome duplication. | 0.559 |
CRH1 | CCW14 | YGR189C | YLR390W-A | Probable glycosidase CRH1; Chitin transglycosylase; functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress. | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | 0.677 |
CRH1 | CIS3 | YGR189C | YJL158C | Probable glycosidase CRH1; Chitin transglycosylase; functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress. | Cell wall mannoprotein CIS3; Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family. | 0.697 |
CRH1 | CWP1 | YGR189C | YKL096W | Probable glycosidase CRH1; Chitin transglycosylase; functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress. | Cell wall mannoprotein that localizes to birth scars of daughter cells; linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; required for propionic acid resistance; Belongs to the SRP1/TIP1 family. | 0.705 |
CRH1 | NCW2 | YGR189C | YLR194C | Probable glycosidase CRH1; Chitin transglycosylase; functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress. | Cell wall biogenesis protein NCW2; Structural constituent of the cell wall; attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress; null mutant is sensitive to the antifungal agent polyhexamethylene biguanide, resistant to zymolyase treatment and has increased chitin deposition. | 0.547 |
CRH1 | PIR3 | YGR189C | YKL163W | Probable glycosidase CRH1; Chitin transglycosylase; functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress. | O-glycosylated covalently-bound cell wall protein; required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway; coding sequence contains length polymorphisms in different strains; PIR3 has a paralog, HSP150, that arose from the whole genome duplication. | 0.665 |
CRH1 | PST1 | YGR189C | YDR055W | Probable glycosidase CRH1; Chitin transglycosylase; functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress. | Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1; PST1 has a paralog, ECM33, that arose from the whole genome duplication; Belongs to the SPS2 family. | 0.744 |