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PRY2 protein (Saccharomyces cerevisiae) - STRING interaction network
"PRY2" - Protein of unknown function in Saccharomyces cerevisiae
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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Score
PRY2Protein of unknown function; Secreted protein required for efficient export of lipids such as acetylated sterols. Acts in detoxification of hydrophobic compounds (329 aa)    
Predicted Functional Partners:
SCW10
Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p; Glucanases possibly play a role in cell expansion during growth, in cell-cell fusion during mating, and in spore release during sporulation (389 aa)
     
   
  0.928
SHE2
RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; RNA-binding protein that binds specific mRNAs including the ASH1 mRNA, coding for a repressor of the HO endonuclease. Part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud and in the daughter cell. Recruits the MYO4-SHE3 complex to the ASH1 mRNA. Recruits also LOC1 and PUF6 to ASH1 mRNA, which are required for translational repression of this mRNA (246 aa)
       
      0.868
SVS1
Cell wall and vacuolar protein, required for wild-type resistance to vanadate; Required for vanadate resistance (260 aa)
     
   
  0.864
PRY1
Protein of unknown function; Secreted protein required for efficient export of lipids such as acetylated sterols. Acts in detoxification of hydrophobic compounds (299 aa)
 
      0.716
CIS3
Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family; Component of the outer cell wall layer. Required for stability of the cell wall and for optimal growth. Required for resistance against several antifungal and cell wall-perturbing agents (227 aa)
     
   
  0.630
KES1
Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex; Lipid transporter involved in lipid countertransport between the Golgi complex and membranes of the endoplasmic reticulum- specifically exchanges sterol with phosphatidylinositol 4-phosphate (PI4P), delivering sterol to the Golgi in exchange for PI4P, which is degraded by the SAC1 phosphatase in the endoplasmic reticulum (PubMed-16136145, PubMed-2216213 [...] (434 aa)
           
  0.579
PIR1
O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle; Component of the outer cell wall layer. Required for stability of the cell wall and for optimal growth. Required for resistance against several antifungal and cell wall-perturbing agents and for tolerance to heat shock (341 aa)
           
  0.483
PIR3
O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway; Component of the outer cell wall layer. Required for stability of the cell wall and for optimal growth. Required for resistance against several antifungal and cell wall-perturbing agents (325 aa)
           
  0.480
FYV10
Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in proteasome-dependent catabolite inactivation of FBPase; contains CTLH domain; plays role in anti-apoptosis; Involved in the proteasome-dependent degradation of fructose-1,6-bisphosphatase and required for survival upon exposure to K1 killer toxin (516 aa)
       
      0.473
VID28
Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm; Has a role in the negative regulation of gluconeogenesis. Required for both proteasome-dependent and vacuolar catabolite degradation of fructose-1,6-bisphosphatase (FBPase) (921 aa)
       
      0.473
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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