node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APD1 | FMP46 | YBR151W | YKR049C | Actin patches distal protein 1; Protein of unknown function; required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus; Belongs to the APD1 family. | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | 0.490 |
APD1 | HER2 | YBR151W | YMR293C | Actin patches distal protein 1; Protein of unknown function; required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus; Belongs to the APD1 family. | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; required for remodeling of ER caused by Hmg2p overexpression; similar to bacterial GatA glutamyl-tRNA amidotransferase. | 0.562 |
APD1 | MRX1 | YBR151W | YER077C | Actin patches distal protein 1; Protein of unknown function; required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus; Belongs to the APD1 family. | MIOREX complex component 1; Protein that associates with mitochondrial ribosome; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; null mutation results in a decrease in plasma membrane electron transport. | 0.589 |
APD1 | MSD1 | YBR151W | YPL104W | Actin patches distal protein 1; Protein of unknown function; required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus; Belongs to the APD1 family. | Aspartate--tRNA ligase, mitochondrial; Mitochondrial aspartyl-tRNA synthetase; required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene. | 0.448 |
APD1 | OSW7 | YBR151W | YFR039C | Actin patches distal protein 1; Protein of unknown function; required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus; Belongs to the APD1 family. | Protein involved in outer spore wall assembly; likely involved directly in dityrosine layer assembly; may be involved in response to high salt and changes in carbon source; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the endoplasmic reticulum; deletion mutant has decreased spore survival in Drosophila feces; OSW7 has a paralog, SHE10, that arose from the whole genome duplication; paralogs are redundant for spore wall dityrosine assembly. | 0.536 |
BSC6 | FMP46 | YOL137W | YKR049C | Bypass of stop codon protein 6; Protein of unknown function with 8 putative transmembrane segments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression. | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | 0.603 |
BSC6 | YIR014W | YOL137W | YIR014W | Bypass of stop codon protein 6; Protein of unknown function with 8 putative transmembrane segments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression. | Vacuole localized DSC protein 1; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; YIR014W is a non-essential gene. | 0.607 |
EGD2 | FMP46 | YHR193C | YKR049C | Alpha subunit of the nascent polypeptide-associated complex (NAC); involved in protein sorting and translocation; associated with cytoplasmic ribosomes. | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | 0.472 |
FMP46 | APD1 | YKR049C | YBR151W | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | Actin patches distal protein 1; Protein of unknown function; required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus; Belongs to the APD1 family. | 0.490 |
FMP46 | BSC6 | YKR049C | YOL137W | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | Bypass of stop codon protein 6; Protein of unknown function with 8 putative transmembrane segments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression. | 0.603 |
FMP46 | EGD2 | YKR049C | YHR193C | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | Alpha subunit of the nascent polypeptide-associated complex (NAC); involved in protein sorting and translocation; associated with cytoplasmic ribosomes. | 0.472 |
FMP46 | HER2 | YKR049C | YMR293C | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; required for remodeling of ER caused by Hmg2p overexpression; similar to bacterial GatA glutamyl-tRNA amidotransferase. | 0.465 |
FMP46 | MOH1 | YKR049C | YBL049W | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | Protein yippee-like MOH1; Protein of unknown function, essential for stationary phase survival; not required for growth on nonfermentable carbon sources; possibly linked with vacuolar transport; Belongs to the yippee family. | 0.514 |
FMP46 | MRX1 | YKR049C | YER077C | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | MIOREX complex component 1; Protein that associates with mitochondrial ribosome; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; null mutation results in a decrease in plasma membrane electron transport. | 0.600 |
FMP46 | MSD1 | YKR049C | YPL104W | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | Aspartate--tRNA ligase, mitochondrial; Mitochondrial aspartyl-tRNA synthetase; required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene. | 0.471 |
FMP46 | OSW7 | YKR049C | YFR039C | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | Protein involved in outer spore wall assembly; likely involved directly in dityrosine layer assembly; may be involved in response to high salt and changes in carbon source; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the endoplasmic reticulum; deletion mutant has decreased spore survival in Drosophila feces; OSW7 has a paralog, SHE10, that arose from the whole genome duplication; paralogs are redundant for spore wall dityrosine assembly. | 0.552 |
FMP46 | TFS1 | YKR049C | YLR178C | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | Inhibitor of carboxypeptidase Y (Prc1p), and Ras GAP (Ira2p); phosphatidylethanolamine-binding protein (PEBP) family member and ortholog of hPEBP1/RKIP, a natural metastasis suppressor; targets to vacuolar membranes during stationary phase; acetylated by NatB N-terminal acetyltransferase; protein abundance increases in response to DNA replication stress. | 0.509 |
FMP46 | YIR014W | YKR049C | YIR014W | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | Vacuole localized DSC protein 1; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; YIR014W is a non-essential gene. | 0.538 |
HER2 | APD1 | YMR293C | YBR151W | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; required for remodeling of ER caused by Hmg2p overexpression; similar to bacterial GatA glutamyl-tRNA amidotransferase. | Actin patches distal protein 1; Protein of unknown function; required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus; Belongs to the APD1 family. | 0.562 |
HER2 | FMP46 | YMR293C | YKR049C | Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial; Subunit of the trimeric GatFAB AmidoTransferase(AdT) complex; involved in the formation of Q-tRNAQ; required for remodeling of ER caused by Hmg2p overexpression; similar to bacterial GatA glutamyl-tRNA amidotransferase. | Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; Belongs to the FMP46 family. | 0.465 |