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KTR2 protein (Saccharomyces cerevisiae) - STRING interaction network
"KTR2" - Mannosyltransferase involved in N-linked protein glycosylation in Saccharomyces cerevisiae
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Known Interactions
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experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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KTR2Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family; Involved in N-linked glycosylation (425 aa)    
Predicted Functional Partners:
MNT4
Putative alpha-1,3-mannosyltransferase, not required for protein O-glycosylation (580 aa)
     
   
  0.505
MNT3
Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation; Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans (630 aa)
           
  0.483
SRL3
Cytoplasmic protein that, when overexpressed, suppresses the lethality of a rad53 null mutation; potential Cdc28p substrate; Weakly suppresses a RAD53 null mutation when overexpressed (246 aa)
     
   
  0.482
PRM5
Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling (318 aa)
     
   
  0.468
NCW2
Structural constituent of the cell wall attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress; Involved in cell wall maintenance (254 aa)
     
   
  0.462
MNN4
Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases; May function as a positive regulator for mannosylphosphate transferase. Is required to mediate mannosylphosphate transfer in both the core and outer chain portions of N-linked oligosaccharides (1178 aa)
           
  0.448
PST1
Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1; Has a partially redundant function to ECM33 in cell wall integrity. May be involved in a repair mechanism activated in response to cell wall damage (444 aa)
           
  0.446
YPS3
Aspartic protease, member of the yapsin family of proteases involved in cell wall growth and maintenance; attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor; Cleaves proteins C-terminally to mono- and paired-basic residues. Required for cell wall integrity (508 aa)
     
   
  0.427
PIR3
O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway; Component of the outer cell wall layer. Required for stability of the cell wall and for optimal growth. Required for resistance against several antifungal and cell wall-perturbing agents (325 aa)
           
  0.412
RLM1
MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p; May function as a transcription factor downstream of MPK1 that is subject to activation by the MPK1 mitogen-activated protein kinase pathway. Binds to the DNA sequence 5’- CTA[TA](4)TAG-3’. At least some RML1 target genes are involved in cell wall biosynthesis (676 aa)
           
  0.400
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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