node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BGL2 | CCW12 | YGR282C | YLR110C | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. | 0.431 |
BGL2 | CCW14 | YGR282C | YLR390W-A | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | 0.756 |
BGL2 | CRH1 | YGR282C | YGR189C | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | Probable glycosidase CRH1; Chitin transglycosylase; functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress. | 0.721 |
BGL2 | CWP1 | YGR282C | YKL096W | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | Cell wall mannoprotein that localizes to birth scars of daughter cells; linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; required for propionic acid resistance; Belongs to the SRP1/TIP1 family. | 0.703 |
BGL2 | GAS1 | YGR282C | YMR307W | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | 1,3-beta-glucanosyltransferase GAS1; Beta-1,3-glucanosyltransferase; required for cell wall assembly and also has a role in transcriptional silencing; localizes to cell surface via a glycosylphosphatidylinositol (GPI) anchor; also found at nuclear periphery; genetic interactions with histone H3 lysine acetyltransferases GCN5 and SAS3 indicate previously unsuspected functions for Gas1 in DNA damage response and cell cycle regulation; Belongs to the glycosyl hydrolase 72 family. | 0.916 |
BGL2 | HSP150 | YGR282C | YJL159W | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | Cell wall mannoprotein HSP150; O-mannosylated heat shock protein; secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation; HSP150 has a paralog, PIR3, that arose from the whole genome duplication. | 0.580 |
BGL2 | PST1 | YGR282C | YDR055W | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1; PST1 has a paralog, ECM33, that arose from the whole genome duplication; Belongs to the SPS2 family. | 0.562 |
BGL2 | SED1 | YGR282C | YDR077W | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | Cell wall protein SED1; Major stress-induced structural GPI-cell wall glycoprotein; associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites; SED1 has a paralog, SPI1, that arose from the whole genome duplication. | 0.464 |
BGL2 | YGP1 | YGR282C | YNL160W | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | Protein YGP1; Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; YGP1 has a paralog, SPS100, that arose from the whole genome duplication; To yeast sporulation-specific protein SPS100. | 0.618 |
CCW12 | BGL2 | YLR110C | YGR282C | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | 0.431 |
CCW12 | CCW14 | YLR110C | YLR390W-A | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | 0.830 |
CCW12 | CWP2 | YLR110C | YKL096W-A | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. | Covalently linked cell wall mannoprotein; major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored. | 0.827 |
CCW12 | GAS1 | YLR110C | YMR307W | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. | 1,3-beta-glucanosyltransferase GAS1; Beta-1,3-glucanosyltransferase; required for cell wall assembly and also has a role in transcriptional silencing; localizes to cell surface via a glycosylphosphatidylinositol (GPI) anchor; also found at nuclear periphery; genetic interactions with histone H3 lysine acetyltransferases GCN5 and SAS3 indicate previously unsuspected functions for Gas1 in DNA damage response and cell cycle regulation; Belongs to the glycosyl hydrolase 72 family. | 0.541 |
CCW12 | HSP150 | YLR110C | YJL159W | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. | Cell wall mannoprotein HSP150; O-mannosylated heat shock protein; secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation; HSP150 has a paralog, PIR3, that arose from the whole genome duplication. | 0.684 |
CCW12 | SED1 | YLR110C | YDR077W | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. | Cell wall protein SED1; Major stress-induced structural GPI-cell wall glycoprotein; associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites; SED1 has a paralog, SPI1, that arose from the whole genome duplication. | 0.862 |
CCW14 | BGL2 | YLR390W-A | YGR282C | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Endo-beta-1,3-glucanase; major protein of the cell wall, involved in cell wall maintenance; involved in incorporation of newly synthesized mannoprotein molecules into the cell wall. | 0.756 |
CCW14 | CCW12 | YLR390W-A | YLR110C | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Cell wall mannoprotein; plays a role in maintenance of newly synthesized areas of cell wall; localizes to periphery of small buds, septum region of larger buds, and shmoo tip; CCW12 has a paralog, YDR134C, that arose from the whole genome duplication. | 0.830 |
CCW14 | CRH1 | YLR390W-A | YGR189C | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Probable glycosidase CRH1; Chitin transglycosylase; functions in the transfer of chitin to beta(1-6) and beta(1-3) glucans in the cell wall; similar and functionally redundant to Utr2; localizes to sites of polarized growth; expression induced by cell wall stress. | 0.677 |
CCW14 | CWP1 | YLR390W-A | YKL096W | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Cell wall mannoprotein that localizes to birth scars of daughter cells; linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; required for propionic acid resistance; Belongs to the SRP1/TIP1 family. | 0.766 |
CCW14 | CWP2 | YLR390W-A | YKL096W-A | Covalently linked cell wall glycoprotein; present in the inner layer of the cell wall; Belongs to the CCW14 family. | Covalently linked cell wall mannoprotein; major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored. | 0.678 |