STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YML007C-AUncharacterized protein YML007C-A, mitochondrial; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria. (36 aa)    
Predicted Functional Partners:
YDR193W
Putative uncharacterized protein YDR193W; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data.
      
 0.871
YDR124W
Uncharacterized protein YDR124W; Putative protein of unknown function; non-essential gene; expression is strongly induced by alpha factor.
      
 0.832
YCL049C
Uncharacterized protein YCL049C; Protein of unknown function; localizes to membrane fraction; YCL049C is not an essential gene.
      
 0.698
SRP40
Suppressor protein SRP40; Nucleolar serine-rich protein; role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140.
      
 0.698
PMP2
Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; protein abundance increases in response to DNA replication stress; PMP2 has a paralog, PMP1, that arose from the whole genome duplication.
   
  
 0.666
YBL039W-B
Uncharacterized protein YBL039W-B; Putative protein of unknown function; mCherry fusion protein localizes to the vacuole.
   
  
 0.642
PUG1
Protoporphyrin uptake protein 1; Plasma membrane protein involved in protoprophyrin and heme transport; roles in the uptake of protoprophyrin IX and the efflux of heme; expression is induced under both low-heme and low-oxygen conditions; member of the fungal lipid-translocating exporter (LTE) family of proteins.
   
  
 0.613
GOT1
Homodimeric protein that is packaged into COPII vesicles; cycles between the ER and Golgi; involved in secretory transport but not directly required for aspects of transport assayed in vitro; may influence membrane composition.
   
  
 0.610
PMP3
Small plasma membrane protein; confers resistance to amphotericin B and is a potential target of this common antifungal drug; related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature; not essential for viability; deletion causes hyperpolarization of the plasma membrane potential; Belongs to the UPF0057 (PMP3) family.
   
  
 0.574
YHR022C-A
Uncharacterized protein YHR022C-A; Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching.
   
    0.485
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.