node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DGR1 | DGR2 | YNL130C-A | YKL121W | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | Protein of unknown function; null mutant is resistant to 2-deoxy-D-glucose and displays abnormally elongated buds; DGR2 has a paralog, YMR102C, that arose from the whole genome duplication; Belongs to the WD repeat DGR2 family. | 0.871 |
DGR1 | GPM1 | YNL130C-A | YKL152C | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | Tetrameric phosphoglycerate mutase; mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.418 |
DGR1 | PYC1 | YNL130C-A | YGL062W | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc2p; mutations in the human homolog are associated with lactic acidosis; PYC1 has a paralog, PYC2, that arose from the whole genome duplication. | 0.414 |
DGR1 | PYC2 | YNL130C-A | YBR218C | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc1p; mutations in the human homolog are associated with lactic acidosis; PYC2 has a paralog, PYC1, that arose from the whole genome duplication. | 0.416 |
DGR1 | YAR035C-A | YNL130C-A | YAR035C-A | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | Uncharacterized protein YAR035C-A; Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; predicted to have a role in cell budding based on computational "guilt by association" analysis. | 0.444 |
DGR1 | YDR118W-A | YNL130C-A | YDR118W-A | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | Uncharacterized protein YDR118W-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified using a combination of expression profiling and mass spectrometry. | 0.447 |
DGR1 | YFR012W-A | YNL130C-A | YFR012W-A | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | Uncharacterized protein YFR012W-A; Putative protein of unknown function; identified by homology. | 0.432 |
DGR1 | YHR086W-A | YNL130C-A | YHR086W-A | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | Uncharacterized protein YHR086W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum and vacuole respectively. | 0.414 |
DGR1 | YML007C-A | YNL130C-A | YML007C-A | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | Uncharacterized protein YML007C-A, mitochondrial; Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria. | 0.422 |
DGR1 | YMR182W-A | YNL130C-A | YMR182W-A | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | Uncharacterized protein YMR182W-A; Putative protein of unknown function. | 0.414 |
DGR2 | DGR1 | YKL121W | YNL130C-A | Protein of unknown function; null mutant is resistant to 2-deoxy-D-glucose and displays abnormally elongated buds; DGR2 has a paralog, YMR102C, that arose from the whole genome duplication; Belongs to the WD repeat DGR2 family. | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | 0.871 |
GPM1 | DGR1 | YKL152C | YNL130C-A | Tetrameric phosphoglycerate mutase; mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | 0.418 |
GPM1 | PYC1 | YKL152C | YGL062W | Tetrameric phosphoglycerate mutase; mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc2p; mutations in the human homolog are associated with lactic acidosis; PYC1 has a paralog, PYC2, that arose from the whole genome duplication. | 0.584 |
GPM1 | PYC2 | YKL152C | YBR218C | Tetrameric phosphoglycerate mutase; mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc1p; mutations in the human homolog are associated with lactic acidosis; PYC2 has a paralog, PYC1, that arose from the whole genome duplication. | 0.654 |
PYC1 | DGR1 | YGL062W | YNL130C-A | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc2p; mutations in the human homolog are associated with lactic acidosis; PYC1 has a paralog, PYC2, that arose from the whole genome duplication. | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | 0.414 |
PYC1 | GPM1 | YGL062W | YKL152C | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc2p; mutations in the human homolog are associated with lactic acidosis; PYC1 has a paralog, PYC2, that arose from the whole genome duplication. | Tetrameric phosphoglycerate mutase; mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.584 |
PYC1 | PYC2 | YGL062W | YBR218C | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc2p; mutations in the human homolog are associated with lactic acidosis; PYC1 has a paralog, PYC2, that arose from the whole genome duplication. | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc1p; mutations in the human homolog are associated with lactic acidosis; PYC2 has a paralog, PYC1, that arose from the whole genome duplication. | 0.999 |
PYC2 | DGR1 | YBR218C | YNL130C-A | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc1p; mutations in the human homolog are associated with lactic acidosis; PYC2 has a paralog, PYC1, that arose from the whole genome duplication. | 2-deoxy-glucose resistant protein 1, mitochondrial; Protein of unknown function; dgr1 null mutant is resistant to 2-deoxy-D-glucose. | 0.416 |
PYC2 | GPM1 | YBR218C | YKL152C | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc1p; mutations in the human homolog are associated with lactic acidosis; PYC2 has a paralog, PYC1, that arose from the whole genome duplication. | Tetrameric phosphoglycerate mutase; mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. | 0.654 |
PYC2 | PYC1 | YBR218C | YGL062W | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc1p; mutations in the human homolog are associated with lactic acidosis; PYC2 has a paralog, PYC1, that arose from the whole genome duplication. | Pyruvate carboxylase isoform; cytoplasmic enzyme that converts pyruvate to oxaloacetate; differentially regulated than isoform Pyc2p; mutations in the human homolog are associated with lactic acidosis; PYC1 has a paralog, PYC2, that arose from the whole genome duplication. | 0.999 |