STRINGSTRING
IRC10 protein (Saccharomyces cerevisiae) - STRING interaction network
"IRC10" - Protein of unknown function in Saccharomyces cerevisiae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IRC10Protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci (586 aa)    
Predicted Functional Partners:
ADY3
Protein required for spore wall formation, thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p; Involved in the pathway that organizes the prospore membrane (PSM) during sporulation. Mediates the assembly of the DON1 ring structure at the leading edge of PSM during meiosis II. May constitute a physical link between SSP1-containing PSM precursors and the spindle pole body (SPB) and may facilitate the recruitment of other factors that are required t [...] (790 aa)
       
 
  0.677
YPR071W
Putative membrane protein; YPR071W is not an essential gene (211 aa)
           
  0.624
TMN2
Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn3p; member of the evolutionarily conserved Transmembrane Nine family of proteins with nine membrane-spanning segments; With EMP70 and TMN3, plays a critical role in the late stages of a nutrient-controlled pathway notably regulating FLO11 gene expression. Acts downstream of RAS2 and TOR. Essential for cell adhesion and filamentous growth. May play a role as effector of cellular copper homeostasis (672 aa)
       
 
  0.620
PAU17
Protein of unknown function, member of the seripauperin multigene family encoded mainly in subtelomeric regions; YLL025W is not an essential gene (124 aa)
           
  0.580
YLR257W
Putative protein of unknown function (321 aa)
           
  0.574
YCL049C
Protein of unknown function; localizes to membrane fraction; YCL049C is not an essential gene (312 aa)
           
  0.514
ABM1
Protein of unknown function, required for normal microtubule organization; Required for normal microtubule organization (123 aa)
           
  0.510
YOL014W
Putative protein of unknown function (124 aa)
           
  0.485
YGL039W
Oxidoreductase shown to reduce carbonyl compounds to chiral alcohols (348 aa)
           
  0.480
DIA3
Protein of unknown function, involved in invasive and pseudohyphal growth (468 aa)
           
  0.451
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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