STRINGSTRING
YPQ1 protein (Saccharomyces cerevisiae) - STRING interaction network
"YPQ1" - Putative protein of unknown function in Saccharomyces cerevisiae
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YPQ1Putative protein of unknown function; predicted to contain six transmembrane domains and is 58% similar to the uncharacterized ORF YBR147W; May function as an amino acid transporter mediating the export of cationic amino acids from the vacuole (308 aa)    
Predicted Functional Partners:
VBA5
Putative transporter of the Major Facilitator Superfamily (MFS); proposed role as a basic amino acid permease based on phylogeny; Transporter required for vacuolar uptake of basic amino acids (582 aa)
           
  0.892
VBA3
Permease of basic amino acids in the vacuolar membrane; Transporter required for vacuolar uptake of histidine and lysine (458 aa)
           
  0.890
BUD13
Subunit of the RES complex, which is required for nuclear pre-mRNA retention and splicing; involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern; Required for efficient splicing and pre-mRNA nuclear retention. May also be involved in positioning the proximal bud pole signal (266 aa)
           
  0.760
ERS1
Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains; Transport cystine out of vacuoles/endodomes (260 aa)
     
   
  0.735
YCL002C
Putative protein of unknown function; YCL002C is not an essential gene (263 aa)
     
   
  0.605
AVT5
Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters; Probable amino acid transporter of unknown specificity (459 aa)
           
  0.580
GCN2
Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex; contributes to DNA damage checkpoint control; Metabolic-stress sensing protein kinase that phosphorylates the alpha subunit of eukaryotic translation initiation factor 2 (eIF-2-alpha/SUI2) on ’Ser-52’ in response to low amino acid availability (PubMed-1739968, PubMed-7623840, PubMed-8798780, PubMed-9528799, PubMed-10983975, PubMed-17202131). Plays a role as an activator of the general amino acid control (GAA [...] (1659 aa)
           
  0.578
NIF3
Protein of unknown function, similar to Listeria monocytogenes major sigma factor (rpoD gene product); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies (288 aa)
           
  0.573
CWC2
Member of the NineTeen Complex (NTC) that contains Prp19p and stabilizes U6 snRNA in catalytic forms of the spliceosome containing U2, U5, and U6 snRNAs; binds directly to U6 snRNA; similar to S. pombe Cwf2; Involved in the first step of pre-mRNA splicing. Required for cell growth and cell cycle control. Plays a role in the levels of the U1, U4, U5 and U6 snRNAs and the maintenance of the U4/U6 snRNA complex. May provide the link between the "nineteen complex" NTC spliceosome protein complex and the spliceosome through the U6 snRNA. Associates predominantly with U6 snRNAs in assembled [...] (339 aa)
           
  0.542
YDR090C
Putative protein of unknown function (310 aa)
           
  0.517
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
Server load: low (15%) [HD]