STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YOR072W-BUncharacterized protein YOR072W-B; Putative protein of unknown function; identified by expression profiling and mass spectrometry. (53 aa)    
Predicted Functional Partners:
MAD1
Coiled-coil protein involved in spindle-assembly checkpoint; required for inhibition of karyopherin/importin Pse1p (aka Kap121p) upon spindle assembly checkpoint arrest; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of anaphase promoting complex activity; forms a complex with Mad2p; gene dosage imbalance between MAD1 and MAD2 leads to chromosome instability; Belongs to the MAD1 family.
    
   0.469
YPR159C-A
Uncharacterized protein YPR159C-A; Protein of unknown function; SWAT-GFP and mCherry fusion proteins localize to the cytosol; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching.
   
    0.453
YJL136W-A
Uncharacterized protein YJL136W-A; Putative protein of unknown function; identified by SAGE.
   
    0.447
YPR108W-A
Uncharacterized protein YPR108W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR.
   
    0.447
YGL006W-A
Uncharacterized protein YGL006W-A; Putative protein of unknown function; identified by SAGE.
   
    0.446
YHR180C-B
Putative uncharacterized protein YHR180C-B; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; completely overlaps the dubious ORF YHR180W-A.
   
    0.445
YDL240C-A
Putative uncharacterized protein YDL240C-A; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; identified by sequence comparison with hemiascomycetous yeast species.
   
    0.444
YMR242W-A
Uncharacterized protein YMR242W-A; Putative protein of unknown function.
   
    0.444
YNL067W-B
Uncharacterized protein YNL067W-B; Putative protein of unknown function.
   
    0.444
Q0143
Putative uncharacterized protein Q0143, mitochondrial; Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data.
   
    0.441
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, Mycoderma cerevisiae, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, yeast
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.