node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AZF1 | MLC2 | YOR113W | YPR188C | Asparagine-rich zinc finger protein AZF1; Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia. | Regulatory light chain for the type II myosin Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring. | 0.492 |
AZF1 | YOR114W | YOR113W | YOR114W | Asparagine-rich zinc finger protein AZF1; Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia. | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | 0.400 |
CEX1 | YOR114W | YOR112W | YOR114W | Cytoplasmic export protein 1; Component of nuclear aminoacylation-dependent tRNA export pathway; cytoplasmic; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a; required for activation of RAN GTPase Gsp1p and dissociation of receptor-tRNA-Gsp1p export complex; recruits Rna1p from cytoplasm to NPC, facilitates Rna1p activation of Gsp1p GTPase activity by enabling Rna1p to gain access to Gsp1p-GTP bound to export receptor tRNA complex. | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | 0.619 |
JLP1 | YOR114W | YLL057C | YOR114W | Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation. | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | 0.477 |
MLC2 | AZF1 | YPR188C | YOR113W | Regulatory light chain for the type II myosin Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring. | Asparagine-rich zinc finger protein AZF1; Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia. | 0.492 |
MLC2 | YOR114W | YPR188C | YOR114W | Regulatory light chain for the type II myosin Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring. | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | 0.522 |
PZF1 | YOR114W | YPR186C | YOR114W | Transcription factor IIIA (TFIIIA); essential DNA binding protein required for transcription of 5S rRNA by RNA polymerase III; not involved in transcription of other RNAP III genes; nine conserved zinc fingers; may also bind 5S rRNA. | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | 0.446 |
TRS33 | YOR114W | YOR115C | YOR114W | Core component of TRAPP complexes I, II and IV; transport protein particle (TRAPP) complexes are related multimeric guanine nucleotide-exchange factor for the GTPase Ypt1p, regulating ER-Golgi traffic (TRAPPI), intra-Golgi traffic (TRAPPII), endosome-Golgi traffic (TRAPPII and III) and autophagy (TRAPPIII, and IV); proposed subunit of a novel complex, TRAPPIV, that may function redundantly with TRAPPIII as a GEF that activates Ypt1 during autophagy; Belongs to the TRAPP small subunits family. BET3 subfamily. | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | 0.405 |
YHL018W | YLR307C-A | YHL018W | YLR307C-A | Putative 4a-hydroxytetrahydrobiopterin dehydratase; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS. | Uncharacterized protein YLR307C-A; Putative protein of unknown function. | 0.602 |
YHL018W | YNR040W | YHL018W | YNR040W | Putative 4a-hydroxytetrahydrobiopterin dehydratase; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS. | Uncharacterized protein YNR040W; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.600 |
YHL018W | YOR114W | YHL018W | YOR114W | Putative 4a-hydroxytetrahydrobiopterin dehydratase; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS. | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | 0.636 |
YLR307C-A | YHL018W | YLR307C-A | YHL018W | Uncharacterized protein YLR307C-A; Putative protein of unknown function. | Putative 4a-hydroxytetrahydrobiopterin dehydratase; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS. | 0.602 |
YLR307C-A | YNR040W | YLR307C-A | YNR040W | Uncharacterized protein YLR307C-A; Putative protein of unknown function. | Uncharacterized protein YNR040W; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.694 |
YLR307C-A | YOR114W | YLR307C-A | YOR114W | Uncharacterized protein YLR307C-A; Putative protein of unknown function. | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | 0.735 |
YNR040W | YHL018W | YNR040W | YHL018W | Uncharacterized protein YNR040W; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Putative 4a-hydroxytetrahydrobiopterin dehydratase; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS. | 0.600 |
YNR040W | YLR307C-A | YNR040W | YLR307C-A | Uncharacterized protein YNR040W; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Uncharacterized protein YLR307C-A; Putative protein of unknown function. | 0.694 |
YNR040W | YOR114W | YNR040W | YOR114W | Uncharacterized protein YNR040W; Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | 0.699 |
YOR114W | AZF1 | YOR114W | YOR113W | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | Asparagine-rich zinc finger protein AZF1; Zinc-finger transcription factor; involved in diauxic shift; in the presence of glucose, activates transcription of genes involved in growth and carbon metabolism; in nonfermentable carbon sources, activates transcription of genes involved in maintenance of cell wall integrity; relocalizes to the cytosol in response to hypoxia. | 0.400 |
YOR114W | CEX1 | YOR114W | YOR112W | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | Cytoplasmic export protein 1; Component of nuclear aminoacylation-dependent tRNA export pathway; cytoplasmic; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a; required for activation of RAN GTPase Gsp1p and dissociation of receptor-tRNA-Gsp1p export complex; recruits Rna1p from cytoplasm to NPC, facilitates Rna1p activation of Gsp1p GTPase activity by enabling Rna1p to gain access to Gsp1p-GTP bound to export receptor tRNA complex. | 0.619 |
YOR114W | JLP1 | YOR114W | YLL057C | Uncharacterized protein YOR114W; Putative protein of unknown function; null mutant is viable. | Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase; involved in sulfonate catabolism for use as a sulfur source; contains sequence that resembles a J domain (typified by the E. coli DnaJ protein); induced by sulphur starvation. | 0.477 |