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PEX27 protein (Saccharomyces cerevisiae) - STRING interaction network
"PEX27" - Peripheral peroxisomal membrane protein involved in controlling peroxisome size and number, interacts with homologous protein Pex25p in Saccharomyces cerevisiae
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Predicted Interactions
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co-expression
protein homology
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PEX27Peripheral peroxisomal membrane protein involved in controlling peroxisome size and number, interacts with homologous protein Pex25p; Required for regulation of peroxisome size and number. Also promotes peroxisome division and biogenesis (376 aa)    
Predicted Functional Partners:
PEX11
Peroxisomal membrane protein required for medium-chain fatty acid oxidation and peroxisome proliferation, possibly by inducing membrane curvature; localization regulated by phosphorylation; transcription regulated by Adr1p and Pip2p-Oaf1p; Involved in peroxisomal proliferation. Promotes peroxisome division and biogenesis (236 aa)
       
 
  0.954
PEX19
Chaperone and import receptor for newly-synthesized class I peroxisomal membrane proteins (PMPs), binds PMPs in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane; Required for proper post-translational import and stabilization of peroxisomal membrane proteins (PMPs). Acts as a cytosolic import receptor for PMPs and delivers them to the docking factor PEX3 at the peroxisomal membrane for subsequent insertion into the membrane. Acts as a chaperone in stabilizing or maintaining PMPs in the lipid bilayer. Directs PEX17, a peripheral co [...] (342 aa)
       
 
  0.908
PEX31
Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p (462 aa)
           
  0.891
PEX30
Peroxisomal integral membrane protein, involved in negative regulation of peroxisome number; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p (523 aa)
           
  0.884
PEX32
Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p (413 aa)
           
  0.795
PEX28
Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p; Involved in the regulation of peroxisome number, size and distribution (579 aa)
           
  0.738
PEX29
Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p; Involved in the regulation of peroxisome number, size and distribution (554 aa)
           
  0.698
PEX3
Peroxisomal membrane protein (PMP) required for proper localization and stability of PMPs; anchors peroxisome retention factor Inp1p at the peroxisomal membrane; interacts with Pex19p; Involved in peroxisome biosynthesis. May function as a receptor protein. Lack of this protein causes the peroxisomal- deficient phenotype and mislocalization in the cytosol of peroxisomal matrix proteins (441 aa)
           
  0.697
PEX25
Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p; Required for regulation of peroxisome size and maintenance. Has a role in the import of peroxisomal matrix proteins. Imports RHO1 into the peroxisome. Also promotes peroxisome division and biogenesis (394 aa)
       
 
0.688
PEX34
Peroxisomal integral membrane protein that regulates peroxisome populations; interacts with Pex11p, Pex25p, and Pex27p to control both constitutive peroxisome division and peroxisome morphology and abundance during peroxisome proliferation; In concert with the three peroxisome divisional factors, PEX11, PEX25 and PEX27, controls peroxisome morphology and abundance under conditions of peroxisome proliferation. Maintains mature peroxisomes in actively dividing cells (144 aa)
       
 
  0.682
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: Candida robusta, Pachytichospora, S. cerevisiae, Saccharomyces, Saccharomyces capensis, Saccharomyces cerevisiae, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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