STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
YOR268CUncharacterized protein YOR268C; Putative protein of unknown function; sporulation is abnormal in homozygous diploid; SWAT-GFP fusion protein localizes to the nucleus; YOR268C is not an essential gene (132 aa)    
Predicted Functional Partners:
YJL052C-A
Uncharacterized protein YJL052C-A; Putative protein of unknown function; identified based on comparison to related yeast species; mCherry fusion protein localizes to the vacuole
      
 0.896
YEL023C
Uncharacterized protein YEL023C; Putative protein of unknown function; expression is increased greatly during sporulation; YEL023C is not an essential gene
      
 0.811
SPE4
Spermine synthase; required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid
      
 0.712
SPO16
Sporulation-specific protein 16; Meiosis-specific protein involved in synaptonemal complex assembly; implicated in regulation of crossover formation; required for sporulation
      
 0.671
SPO20
Sporulation-specific protein 20; Meiosis-specific subunit of the t-SNARE complex; required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; binds to phosphatidic acid; SNAP-25 homolog
      
 0.671
YBR225W
Uncharacterized protein YBR225W; Putative protein of unknown function; non-essential gene identified in a screen for mutants affected in mannosylphophorylation of cell wall components
      
 0.613
DSC2
Uncharacterized membrane protein YOL073C; Multi-transmembrane subunit of the DSC ubiquitin ligase complex; similar in sequence to rhomboid pseudoproteases Der1p and UBAC2 that function in ERAD; ortholog of fission yeast dsc2
      
 0.574
YLR345W
Bifunctional fructose-2,6-bisphosphate 2-phosphatase/6-phosphofructo-2-kinase; Putative 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase YLR345W; Similar to 6-phosphofructo-2-kinase enzymes; mRNA expression is repressed by the Rfx1p-Tup1p-Ssn6p repressor complex; YLR345W is not an essential gene; In the C-terminal section; belongs to the phosphoglycerate mutase family
      
 0.521
MRPS9
Mitochondrial 37s ribosomal protein mrps9; Mitochondrial ribosomal protein of the small subunit
    
 
 0.404
Your Current Organism:
Saccharomyces cerevisiae
NCBI taxonomy Id: 4932
Other names: ATCC 18824, Candida robusta, NRRL Y-12632, S. cerevisiae, Saccharomyces capensis, Saccharomyces italicus, Saccharomyces oviformis, Saccharomyces uvarum var. melibiosus, lager beer yeast, yeast
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.