node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ATF1 | YOR376W-A | YOR377W | YOR376W-A | Alcohol O-acetyltransferase 1; Alcohol acetyltransferase; responsible for the major part of volatile acetate ester production during fermentation; main enzyme involved in terpenyl acetate synthesis; potential roles in lipid and sterol metabolism. | Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.515 |
CWC21 | YOR376W-A | YDR482C | YOR376W-A | Pre-mRNA-splicing factor CWC21; Protein involved in RNA splicing by the spliceosome; component of a complex containing Cef1p; interacts genetically with ISY1 and BUD13; may bind RNA; has similarity to S. pombe Cwf21p; Belongs to the CWC21 family. | Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.636 |
LPL1 | SMA2 | YOR059C | YML066C | Lipid droplet phospholipase 1; Phospholipase; contains lipase specific GXSXG motif; maintains lipid droplet (LD) morphology; induced by transcription factor Rpn4p; protein abundance increases in response to DNA replication stress. | Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; Belongs to the SMA2 family. | 0.414 |
LPL1 | YIL165C | YOR059C | YIL165C | Lipid droplet phospholipase 1; Phospholipase; contains lipase specific GXSXG motif; maintains lipid droplet (LD) morphology; induced by transcription factor Rpn4p; protein abundance increases in response to DNA replication stress. | Putative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. | 0.495 |
LPL1 | YOR376W-A | YOR059C | YOR376W-A | Lipid droplet phospholipase 1; Phospholipase; contains lipase specific GXSXG motif; maintains lipid droplet (LD) morphology; induced by transcription factor Rpn4p; protein abundance increases in response to DNA replication stress. | Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.792 |
MAK11 | YOR376W-A | YKL021C | YOR376W-A | Protein involved in an early step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats. | Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.597 |
NIT1 | YIL165C | YIL164C | YIL165C | Putative nitrilase-like protein NIT1; Nitrilase; member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. | Putative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. | 0.999 |
NIT1 | YOR376W-A | YIL164C | YOR376W-A | Putative nitrilase-like protein NIT1; Nitrilase; member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. | Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.690 |
QCR6 | YOR376W-A | YFR033C | YOR376W-A | Subunit 6 of the ubiquinol cytochrome-c reductase complex; the complex, also known as the cytochrome bc(1) complex or Complex III, is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1; may be loosely associated with the complex since it is easily released into the intermembrane space; Belongs to the UQCRH/QCR6 family. | Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.536 |
SLD7 | YOR376W-A | YOR060C | YOR376W-A | Mitochondrial morphogenesis protein SLD7; Protein with a role in chromosomal DNA replication; interacts with Sld3p and reduces its affinity for Cdc45p; deletion mutant has aberrant mitochondria. | Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.550 |
SMA2 | LPL1 | YML066C | YOR059C | Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; Belongs to the SMA2 family. | Lipid droplet phospholipase 1; Phospholipase; contains lipase specific GXSXG motif; maintains lipid droplet (LD) morphology; induced by transcription factor Rpn4p; protein abundance increases in response to DNA replication stress. | 0.414 |
SMA2 | SPO77 | YML066C | YLR341W | Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; Belongs to the SMA2 family. | Sporulation-specific protein 77; Meiosis-specific protein of unknown function; required for spore wall formation during sporulation and for timely prospore membrane closure along with SPS1; required with Sps1p for phosphorylation and turnover of Ssp1p; dispensable for both nuclear divisions during meiosis. | 0.878 |
SMA2 | YIL165C | YML066C | YIL165C | Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; Belongs to the SMA2 family. | Putative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. | 0.416 |
SMA2 | YOR376W-A | YML066C | YOR376W-A | Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; Belongs to the SMA2 family. | Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.700 |
SPO77 | SMA2 | YLR341W | YML066C | Sporulation-specific protein 77; Meiosis-specific protein of unknown function; required for spore wall formation during sporulation and for timely prospore membrane closure along with SPS1; required with Sps1p for phosphorylation and turnover of Ssp1p; dispensable for both nuclear divisions during meiosis. | Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; Belongs to the SMA2 family. | 0.878 |
SPO77 | YOR376W-A | YLR341W | YOR376W-A | Sporulation-specific protein 77; Meiosis-specific protein of unknown function; required for spore wall formation during sporulation and for timely prospore membrane closure along with SPS1; required with Sps1p for phosphorylation and turnover of Ssp1p; dispensable for both nuclear divisions during meiosis. | Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.516 |
YIL165C | LPL1 | YIL165C | YOR059C | Putative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. | Lipid droplet phospholipase 1; Phospholipase; contains lipase specific GXSXG motif; maintains lipid droplet (LD) morphology; induced by transcription factor Rpn4p; protein abundance increases in response to DNA replication stress. | 0.495 |
YIL165C | NIT1 | YIL165C | YIL164C | Putative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. | Putative nitrilase-like protein NIT1; Nitrilase; member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. | 0.999 |
YIL165C | SMA2 | YIL165C | YML066C | Putative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. | Meiosis-specific prospore membrane protein; required to produce bending force necessary for proper assembly of the prospore membrane during sporulation; Belongs to the SMA2 family. | 0.416 |
YIL165C | YOR376W-A | YIL165C | YOR376W-A | Putative protein of unknown function; mutant exhibits mitophagy defects; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene; Belongs to the carbon-nitrogen hydrolase superfamily. Nitrilase family. | Uncharacterized protein YOR376W-A; Putative protein of unknown function; identified by fungal homology and RT-PCR. | 0.793 |