node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AIM17 | FMP40 | YHL021C | YPL222W | Probable oxidoreductase AIM17; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss; Belongs to the gamma-BBH/TMLD family. | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.725 |
AIM17 | GOR1 | YHL021C | YNL274C | Probable oxidoreductase AIM17; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss; Belongs to the gamma-BBH/TMLD family. | Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.828 |
AIM17 | OM45 | YHL021C | YIL136W | Probable oxidoreductase AIM17; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss; Belongs to the gamma-BBH/TMLD family. | Mitochondrial outer membrane protein of unknown function; major constituent of the outer membrane, extending into the intermembrane space; interacts with porin (Por1p) and with Om14p; imported via the presequence pathway involving the TOM and TIM23 complexes, then assembled in the outer membrane by Mim1p; protein abundance increases in response to DNA replication stress. | 0.508 |
FLC1 | FMP40 | YPL221W | YPL222W | Flavin carrier protein 1; Flavin adenine dinucleotide transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; FLC1 has a paralog, FLC3, that arose from the whole genome duplication; Belongs to the transient receptor potential (TRP) ion channel family. | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.562 |
FMP40 | AIM17 | YPL222W | YHL021C | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Probable oxidoreductase AIM17; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss; Belongs to the gamma-BBH/TMLD family. | 0.725 |
FMP40 | FLC1 | YPL222W | YPL221W | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Flavin carrier protein 1; Flavin adenine dinucleotide transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance; FLC1 has a paralog, FLC3, that arose from the whole genome duplication; Belongs to the transient receptor potential (TRP) ion channel family. | 0.562 |
FMP40 | GCD11 | YPL222W | YER025W | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Gamma subunit of the translation initiation factor eIF2; involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met; mutations in human ortholog cause X-linked intellectual disability (XLID); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.497 |
FMP40 | GOR1 | YPL222W | YNL274C | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | 0.470 |
FMP40 | GPX1 | YPL222W | YKL026C | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Glutathione peroxidase-like peroxiredoxin 1; Phospholipid hydroperoxide glutathione peroxidase; induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress; GPX1 has a paralog, HYR1, that arose from the whole genome duplication. | 0.517 |
FMP40 | KGD1 | YPL222W | YIL125W | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 2-oxoglutarate dehydrogenase, mitochondrial; Subunit of the mitochondrial alpha-ketoglutarate dehydrogenase complex; catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA. | 0.511 |
FMP40 | MXR2 | YPL222W | YCL033C | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Methionine-R-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan. | 0.607 |
FMP40 | NAB3 | YPL222W | YPL190C | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | RNA-binding protein, subunit of Nrd1 complex (Nrd1p-Nab3p-Sen1p); complex interacts with exosome to mediate 3'-end formation of some mRNAs, snRNAs, snoRNAs, and CUTs; required for termination of non-poly(A) transcripts and efficient splicing; Nrd1-Nab3 pathway appears to have a role in rapid suppression of some genes when cells are shifted to poor growth conditions, indicating role for Nrd1-Nab3 in regulating cellular response to nutrient availability. | 0.520 |
FMP40 | OM45 | YPL222W | YIL136W | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Mitochondrial outer membrane protein of unknown function; major constituent of the outer membrane, extending into the intermembrane space; interacts with porin (Por1p) and with Om14p; imported via the presequence pathway involving the TOM and TIM23 complexes, then assembled in the outer membrane by Mim1p; protein abundance increases in response to DNA replication stress. | 0.518 |
FMP40 | YPL222C-A | YPL222W | YPL222C-A | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | Putative uncharacterized protein YPL222C-A; Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching. | 0.804 |
GCD11 | FMP40 | YER025W | YPL222W | Gamma subunit of the translation initiation factor eIF2; involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met; mutations in human ortholog cause X-linked intellectual disability (XLID); Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.497 |
GOR1 | AIM17 | YNL274C | YHL021C | Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Probable oxidoreductase AIM17; Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays reduced frequency of mitochondrial genome loss; Belongs to the gamma-BBH/TMLD family. | 0.828 |
GOR1 | FMP40 | YNL274C | YPL222W | Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.470 |
GOR1 | MXR2 | YNL274C | YCL033C | Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Methionine-R-sulfoxide reductase; involved in the response to oxidative stress; protects iron-sulfur clusters from oxidative inactivation along with MXR1; involved in the regulation of lifespan. | 0.472 |
GOR1 | OM45 | YNL274C | YIL136W | Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; protein abundance increases in response to DNA replication stress; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. | Mitochondrial outer membrane protein of unknown function; major constituent of the outer membrane, extending into the intermembrane space; interacts with porin (Por1p) and with Om14p; imported via the presequence pathway involving the TOM and TIM23 complexes, then assembled in the outer membrane by Mim1p; protein abundance increases in response to DNA replication stress. | 0.591 |
GPX1 | FMP40 | YKL026C | YPL222W | Glutathione peroxidase-like peroxiredoxin 1; Phospholipid hydroperoxide glutathione peroxidase; induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress; GPX1 has a paralog, HYR1, that arose from the whole genome duplication. | Protein adenylyltransferase SelO, mitochondrial; Putative protein of unknown function; proposed to be involved in responding to environmental stresses; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies. | 0.517 |