node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
BLI1 | KEL3 | YKL061W | YPL263C | Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to the endosome. | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | 0.697 |
BLI1 | KXD1 | YKL061W | YGL079W | Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to the endosome. | Subunit of the BLOC-1 complex involved in endosomal maturation; null mutant is sensitive to drug inducing secretion of vacuolar cargo; GFP-fusion protein localizes to the endosome; Belongs to the KXD1 family. | 0.998 |
BLI1 | SNN1 | YKL061W | YNL086W | Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to the endosome. | Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to endosomes. | 0.999 |
DOS2 | KEL3 | YDR068W | YPL263C | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | 0.617 |
DOS2 | YER134C | YDR068W | YER134C | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | Magnesium-dependent acid phosphatase; member of the haloacid dehalogenase superfamily; non-essential gene; Belongs to the HAD-like hydrolase superfamily. | 0.905 |
KEL3 | BLI1 | YPL263C | YKL061W | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to the endosome. | 0.697 |
KEL3 | DOS2 | YPL263C | YDR068W | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm. | 0.617 |
KEL3 | KXD1 | YPL263C | YGL079W | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | Subunit of the BLOC-1 complex involved in endosomal maturation; null mutant is sensitive to drug inducing secretion of vacuolar cargo; GFP-fusion protein localizes to the endosome; Belongs to the KXD1 family. | 0.755 |
KEL3 | MAK21 | YPL263C | YDR060W | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | Ribosome biogenesis protein MAK21; Constituent of 66S pre-ribosomal particles; required for large (60S) ribosomal subunit biogenesis; acts as part of a Mak21p-Noc2p-Rrp5p module that associates with nascent pre-rRNA during transcription and has a role in bigenesis of the large ribosomal subunit; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein. | 0.617 |
KEL3 | NPL3 | YPL263C | YDR432W | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | Nucleolar protein 3; RNA-binding protein; promotes elongation, regulates termination, and carries poly(A) mRNA from nucleus to cytoplasm; represses translation initiation by binding eIF4G; required for pre-mRNA splicing; interacts with E3 ubiquitin ligase Bre1p, linking histone ubiquitination to mRNA processing; may have role in telomere maintenance; dissociation from mRNAs promoted by Mtr10p; phosphorylated by Sky1p in cytoplasm; protein abundance increases in response to DNA replication stress. | 0.695 |
KEL3 | PAB1 | YPL263C | YER165W | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | Polyadenylate-binding protein, cytoplasmic and nuclear; Poly(A) binding protein; part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G; stimulates, but is not required for the deadenylation activity of the Pan2p-Pan3p poly(A)-ribonuclease complex; Belongs to the polyadenylate-binding protein type-1 family. | 0.665 |
KEL3 | PNO1 | YPL263C | YOR145C | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | Pre-rRNA-processing protein PNO1; Essential nucleolar protein required for pre-18S rRNA processing; interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain. | 0.748 |
KEL3 | PUS9 | YPL263C | YDL036C | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | Mitochondrial tRNA:pseudouridine synthase; catalyzes the formation of pseudouridine at position 32 in mitochondrial tRNAs; contains an N-terminal mitochondrial targeting sequence; PUS9 has a paralog, RIB2, that arose from the whole genome duplication. | 0.623 |
KEL3 | SNN1 | YPL263C | YNL086W | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to endosomes. | 0.608 |
KEL3 | YER134C | YPL263C | YER134C | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | Magnesium-dependent acid phosphatase; member of the haloacid dehalogenase superfamily; non-essential gene; Belongs to the HAD-like hydrolase superfamily. | 0.699 |
KXD1 | BLI1 | YGL079W | YKL061W | Subunit of the BLOC-1 complex involved in endosomal maturation; null mutant is sensitive to drug inducing secretion of vacuolar cargo; GFP-fusion protein localizes to the endosome; Belongs to the KXD1 family. | Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to the endosome. | 0.998 |
KXD1 | KEL3 | YGL079W | YPL263C | Subunit of the BLOC-1 complex involved in endosomal maturation; null mutant is sensitive to drug inducing secretion of vacuolar cargo; GFP-fusion protein localizes to the endosome; Belongs to the KXD1 family. | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | 0.755 |
KXD1 | SNN1 | YGL079W | YNL086W | Subunit of the BLOC-1 complex involved in endosomal maturation; null mutant is sensitive to drug inducing secretion of vacuolar cargo; GFP-fusion protein localizes to the endosome; Belongs to the KXD1 family. | Subunit of the BLOC-1 complex involved in endosomal maturation; interacts with Msb3p; green fluorescent protein (GFP)-fusion protein localizes to endosomes. | 0.990 |
MAK21 | KEL3 | YDR060W | YPL263C | Ribosome biogenesis protein MAK21; Constituent of 66S pre-ribosomal particles; required for large (60S) ribosomal subunit biogenesis; acts as part of a Mak21p-Noc2p-Rrp5p module that associates with nascent pre-rRNA during transcription and has a role in bigenesis of the large ribosomal subunit; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein. | Kelch repeat-containing protein 3; Cytoplasmic protein of unknown function. | 0.617 |
MAK21 | PNO1 | YDR060W | YOR145C | Ribosome biogenesis protein MAK21; Constituent of 66S pre-ribosomal particles; required for large (60S) ribosomal subunit biogenesis; acts as part of a Mak21p-Noc2p-Rrp5p module that associates with nascent pre-rRNA during transcription and has a role in bigenesis of the large ribosomal subunit; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein. | Pre-rRNA-processing protein PNO1; Essential nucleolar protein required for pre-18S rRNA processing; interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain. | 0.861 |