node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
APE2 | PTC7 | YKL157W | YHR076W | Aminopeptidase 2, mitochondrial; Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; APE2 has a paralog, AAP1, that arose from the whole genome duplication; Belongs to the peptidase M1 family. | Type 2C serine/threonine protein phosphatase (PP2C); alternatively spliced to create two mRNA isoforms; protein from spliced form localizes to the mitochondria while the one from the unspliced form is localized to the nuclear envelope; activates coenzyme Q6 biosynthesis by dephosphorylation of demethoxy-Q6 hydroxylase Coq7p. | 0.442 |
APE2 | YPR202W | YKL157W | YPR202W | Aminopeptidase 2, mitochondrial; Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; APE2 has a paralog, AAP1, that arose from the whole genome duplication; Belongs to the peptidase M1 family. | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | 0.518 |
MRM2 | YPR202W | YGL136C | YPR202W | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | 0.446 |
PTC7 | APE2 | YHR076W | YKL157W | Type 2C serine/threonine protein phosphatase (PP2C); alternatively spliced to create two mRNA isoforms; protein from spliced form localizes to the mitochondria while the one from the unspliced form is localized to the nuclear envelope; activates coenzyme Q6 biosynthesis by dephosphorylation of demethoxy-Q6 hydroxylase Coq7p. | Aminopeptidase 2, mitochondrial; Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; APE2 has a paralog, AAP1, that arose from the whole genome duplication; Belongs to the peptidase M1 family. | 0.442 |
PTC7 | YPR202W | YHR076W | YPR202W | Type 2C serine/threonine protein phosphatase (PP2C); alternatively spliced to create two mRNA isoforms; protein from spliced form localizes to the mitochondria while the one from the unspliced form is localized to the nuclear envelope; activates coenzyme Q6 biosynthesis by dephosphorylation of demethoxy-Q6 hydroxylase Coq7p. | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | 0.412 |
YLR464W | YPR202W | YLR464W | YPR202W | Putative protein of unknown function; intron is predicted but not detected experimentally; YLR464W overlaps the verified gene YRF1-4/YLR466W and two dubious ORFs YLR463C and YLR465C. | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | 0.733 |
YLR464W | YRF1-4 | YLR464W | YLR466W | Putative protein of unknown function; intron is predicted but not detected experimentally; YLR464W overlaps the verified gene YRF1-4/YLR466W and two dubious ORFs YLR463C and YLR465C. | Y' element ATP-dependent helicase protein 1 copy 4; Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p. | 0.941 |
YPR202W | APE2 | YPR202W | YKL157W | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | Aminopeptidase 2, mitochondrial; Aminopeptidase yscII; may have a role in obtaining leucine from dipeptide substrates; APE2 has a paralog, AAP1, that arose from the whole genome duplication; Belongs to the peptidase M1 family. | 0.518 |
YPR202W | MRM2 | YPR202W | YGL136C | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | Mitochondrial 2' O-ribose methyltransferase; required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. | 0.446 |
YPR202W | PTC7 | YPR202W | YHR076W | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | Type 2C serine/threonine protein phosphatase (PP2C); alternatively spliced to create two mRNA isoforms; protein from spliced form localizes to the mitochondria while the one from the unspliced form is localized to the nuclear envelope; activates coenzyme Q6 biosynthesis by dephosphorylation of demethoxy-Q6 hydroxylase Coq7p. | 0.412 |
YPR202W | YLR464W | YPR202W | YLR464W | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | Putative protein of unknown function; intron is predicted but not detected experimentally; YLR464W overlaps the verified gene YRF1-4/YLR466W and two dubious ORFs YLR463C and YLR465C. | 0.733 |
YPR202W | YPR203W | YPR202W | YPR203W | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | Putative protein of unknown function; Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily. | 0.928 |
YPR202W | YPR204C-A | YPR202W | YPR204C-A | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching. | 0.928 |
YPR202W | YPR204W | YPR202W | YPR204W | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | DNA helicase encoded within the telomeric Y' element; Y' -helicase protein 1. | 0.893 |
YPR202W | YRF1-4 | YPR202W | YLR466W | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | Y' element ATP-dependent helicase protein 1 copy 4; Helicase encoded by the Y' element of subtelomeric regions; highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p. | 0.637 |
YPR203W | YPR202W | YPR203W | YPR202W | Putative protein of unknown function; Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily. | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | 0.928 |
YPR203W | YPR204C-A | YPR203W | YPR204C-A | Putative protein of unknown function; Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily. | Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching. | 0.928 |
YPR203W | YPR204W | YPR203W | YPR204W | Putative protein of unknown function; Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily. | DNA helicase encoded within the telomeric Y' element; Y' -helicase protein 1. | 0.895 |
YPR204C-A | YPR202W | YPR204C-A | YPR202W | Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching. | Putative protein of unknown function; similar to telomere-encoded helicases; down-regulated at low calcium levels; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo. | 0.928 |
YPR204C-A | YPR203W | YPR204C-A | YPR203W | Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching. | Putative protein of unknown function; Belongs to the helicase family. Yeast subtelomeric Y' repeat subfamily. | 0.928 |