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DRE2 protein (Torulaspora delbrueckii) - STRING interaction network
"DRE2" - Fe-S cluster assembly protein DRE2 in Torulaspora delbrueckii
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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DRE2Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein TAH18. Has anti-apoptotic effects in the cell. Involved in negative control of H(2)O(2)-induced cell death (302 aa)    
Predicted Functional Partners:
TAH18
NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe-S cluster of DRE2. Positively controls H(2)O(2)-induced cell death; In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family (626 aa)
     
 
  0.979
XP_003678667.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae GRX3 (YDR098C) and GRX4 (YER174C); ancestral locus Anc_8.240 (242 aa)
       
 
  0.970
NBP35
Cytosolic Fe-S cluster assembly factor TDEL0G01640; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export; Belongs to the Mrp/NBP35 ATP-binding proteins family. NU [...] (333 aa)
     
 
  0.939
XP_003681493.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae NAR1 (YNL240C); ancestral locus Anc_2.4; Belongs to the NARF family (476 aa)
     
 
  0.893
XP_003679458.1
Glutaredoxin; Similar to Saccharomyces cerevisiae GRX5 (YPL059W); ancestral locus Anc_8.519; Belongs to the glutaredoxin family. Monothiol subfamily (145 aa)
     
 
  0.874
XP_003683498.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae YAL046C; ancestral locus Anc_7.23; Belongs to the BolA/IbaG family (102 aa)
     
 
  0.860
CFD1
Cytosolic Fe-S cluster assembly factor CFD1; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NBP35-CFD1 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins. Required for biogenesis and export of both ribosomal subunits, which may reflect a role in assembly of the Fe/S clusters in RLI1, a protein which performs rRNA processing and ribosome export; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD [...] (282 aa)
     
 
  0.853
XP_003681393.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae YGL220W; ancestral locus Anc_3.530; Belongs to the BolA/IbaG family (84 aa)
     
 
  0.822
XP_003683497.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae YAL044W-A; ancestral locus Anc_7.24; Belongs to the BolA/IbaG family (124 aa)
     
 
  0.814
XP_003680550.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae MET18 (YIL128W); ancestral locus Anc_2.233 (1022 aa)
     
   
  0.776
Your Current Organism:
Torulaspora delbrueckii
NCBI taxonomy Id: 4950
Other names: Candida colliculosa, Saccharomyces delbrueckii, Saccharomyces fermentati, Saccharomyces rosei, T. delbrueckii, Torulaspora delbrueckii, Torulaspora sp. R3DFM2, WM 821
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