Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein; Similar to Saccharomyces cerevisiae PIN2 (YOR104W); ancestral locus Anc_2.179 (215 aa)
Predicted Functional Partners:
Uncharacterized protein; Similar to Saccharomyces cerevisiae PIN4 (YBL051C); ancestral locus Anc_7.370 (632 aa)
Phospholipid-transporting ATPase; Similar to Saccharomyces cerevisiae DRS2 (YAL026C); ancestral locus Anc_7.72; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily (1334 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae NEW1 (YPL226W); ancestral locus Anc_6.251 (1180 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae STE18 (YJR086W); ancestral locus Anc_7.455 (95 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae LSM4 (YER112W); ancestral locus Anc_7.410 (175 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae NUP100 (YKL068W) and NUP116 (YMR047C); ancestral locus Anc_2.610 (1165 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae SWI1 (YPL016W); ancestral locus Anc_8.472 (1197 aa)
Uncharacterized protein (548 aa)
Protein URE2; Plays an important role in the cellular response to the nitrogen source (358 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae LSB1 (YGR136W) and PIN3 (YPR154W); ancestral locus Anc_3.501 (201 aa)