Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein; Similar to Saccharomyces cerevisiae KHA1 (YJL094C); ancestral locus Anc_1.272 (869 aa)
Predicted Functional Partners:
Uncharacterized protein; Similar to Saccharomyces cerevisiae NHA1 (YLR138W); ancestral locus Anc_8.341 (956 aa)
Sodium/hydrogen exchanger; Similar to Saccharomyces cerevisiae NHX1 (YDR456W); ancestral locus Anc_5.573; Belongs to the monovalent cation-proton antiporter 1 (CPA1) transporter (TC 2.A.36) family (625 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae TOK1 (YJL093C); ancestral locus Anc_1.273; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family (668 aa)
Potassium transport protein; Similar to Saccharomyces cerevisiae TRK1 (YJL129C) and TRK2 (YKR050W); ancestral locus Anc_1.224; Belongs to the TrkH potassium transport family (1213 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae VNX1 (YNL321W); ancestral locus Anc_3.19; Belongs to the Ca(2+)-cation antiporter (CaCA) (TC 2.A.19) family (938 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae YLH47 (YPR125W); ancestral locus Anc_3.461 (426 aa)
Uncharacterized protein; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family (1091 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae ENA1 (YDR040C); ancestral locus Anc_3.276; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family (1075 aa)
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium (944 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae TFP1 (YDL185W); ancestral locus Anc_7.300 (617 aa)