Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Sulfhydryl oxidase; Similar to Saccharomyces cerevisiae ERV1 (YGR029W); ancestral locus Anc_4.167 (178 aa)
Predicted Functional Partners:
Uncharacterized protein; Similar to Saccharomyces cerevisiae MIA40 (YKL195W); ancestral locus Anc_4.302 (347 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae MRS11 (YHR005C-A); ancestral locus Anc_2.645 (94 aa)
Mitochondrial inner membrane protease ATP23; Has a dual role in the assembly of mitochondrial ATPase (248 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae TIM9 (YEL020W-A); ancestral locus Anc_1.452; Belongs to the small Tim family (87 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae ERO1 (YML130C); ancestral locus Anc_8.877 (560 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae COX19 (YLL018C-A); ancestral locus Anc_4.43 (86 aa)
Uncharacterized protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain (110 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae HOT13 (YKL084W); ancestral locus Anc_2.640 (103 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae TIM13 (YGR181W); ancestral locus Anc_5.188; Belongs to the small Tim family (102 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae TAD2 (YJL035C); ancestral locus Anc_5.238 (240 aa)