Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein; Similar to Saccharomyces cerevisiae ENA1 (YDR040C); ancestral locus Anc_3.276; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family (1075 aa)
Predicted Functional Partners:
Uncharacterized protein; Similar to Saccharomyces cerevisiae NHA1 (YLR138W); ancestral locus Anc_8.341 (956 aa)
Serine/threonine-protein phosphatase; Similar to Saccharomyces cerevisiae PPZ2 (YDR436W) and PPZ1 (YML016C); ancestral locus Anc_5.548 (674 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae KHA1 (YJL094C); ancestral locus Anc_1.272 (869 aa)
Sodium/hydrogen exchanger; Similar to Saccharomyces cerevisiae NHX1 (YDR456W); ancestral locus Anc_5.573; Belongs to the monovalent cation-proton antiporter 1 (CPA1) transporter (TC 2.A.36) family (625 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae CRZ1 (YNL027W); ancestral locus Anc_2.303 (506 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae CNB1 (YKL190W); ancestral locus Anc_4.292 (175 aa)
ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane (546 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae CCH1 (YGR217W); ancestral locus Anc_5.113 (1976 aa)
Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium (1166 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae CMD1 (YBR109C); ancestral locus Anc_3.360 (147 aa)