| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| HAM1 | OLA1 | XP_003682063.1 | XP_003681193.1 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5’-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | 0.532 |
| HAM1 | XP_003680901.1 | XP_003682063.1 | XP_003680901.1 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5’-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions | Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.959 |
| OLA1 | HAM1 | XP_003681193.1 | XP_003682063.1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5’-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions | 0.532 |
| OLA1 | XP_003679380.1 | XP_003681193.1 | XP_003679380.1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | Proteasome endopeptidase complex; Similar to Saccharomyces cerevisiae PRE8 (YML092C); ancestral locus Anc_8.871; Belongs to the peptidase T1A family | 0.627 |
| OLA1 | XP_003679479.1 | XP_003681193.1 | XP_003679479.1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | Uncharacterized protein; Similar to Saccharomyces cerevisiae CAM1 (YPL048W); ancestral locus Anc_8.498 | 0.541 |
| OLA1 | XP_003680069.1 | XP_003681193.1 | XP_003680069.1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | Uncharacterized protein; Similar to Saccharomyces cerevisiae TEF4 (YKL081W); ancestral locus Anc_2.635 | 0.541 |
| OLA1 | XP_003680514.1 | XP_003681193.1 | XP_003680514.1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | Uncharacterized protein; Similar to Saccharomyces cerevisiae ARP5 (YNL059C); ancestral locus Anc_2.248; Belongs to the actin family | 0.567 |
| OLA1 | XP_003680901.1 | XP_003681193.1 | XP_003680901.1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.611 |
| OLA1 | XP_003681865.1 | XP_003681193.1 | XP_003681865.1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | Uncharacterized protein; Similar to Saccharomyces cerevisiae DNM1 (YLL001W); ancestral locus Anc_5.218; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family | 0.690 |
| OLA1 | XP_003682672.1 | XP_003681193.1 | XP_003682672.1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | Uncharacterized protein; Similar to Saccharomyces cerevisiae MTG2 (YHR168W); ancestral locus Anc_5.70 | 0.827 |
| OLA1 | XP_003683026.1 | XP_003681193.1 | XP_003683026.1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | Uncharacterized protein; Similar to Saccharomyces cerevisiae SGT2 (YOR007C); ancestral locus Anc_6.21 | 0.598 |
| OLA1 | XP_003683128.1 | XP_003681193.1 | XP_003683128.1 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | Uncharacterized protein; Similar to Saccharomyces cerevisiae GCD11 (YER025W); ancestral locus Anc_7.513 | 0.570 |
| XP_003679380.1 | OLA1 | XP_003679380.1 | XP_003681193.1 | Proteasome endopeptidase complex; Similar to Saccharomyces cerevisiae PRE8 (YML092C); ancestral locus Anc_8.871; Belongs to the peptidase T1A family | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | 0.627 |
| XP_003679380.1 | XP_003680901.1 | XP_003679380.1 | XP_003680901.1 | Proteasome endopeptidase complex; Similar to Saccharomyces cerevisiae PRE8 (YML092C); ancestral locus Anc_8.871; Belongs to the peptidase T1A family | Inosine-5’-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5’-phosphate (IMP) to xanthosine 5’-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth | 0.532 |
| XP_003679380.1 | XP_003683026.1 | XP_003679380.1 | XP_003683026.1 | Proteasome endopeptidase complex; Similar to Saccharomyces cerevisiae PRE8 (YML092C); ancestral locus Anc_8.871; Belongs to the peptidase T1A family | Uncharacterized protein; Similar to Saccharomyces cerevisiae SGT2 (YOR007C); ancestral locus Anc_6.21 | 0.652 |
| XP_003679479.1 | OLA1 | XP_003679479.1 | XP_003681193.1 | Uncharacterized protein; Similar to Saccharomyces cerevisiae CAM1 (YPL048W); ancestral locus Anc_8.498 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | 0.541 |
| XP_003679479.1 | XP_003680069.1 | XP_003679479.1 | XP_003680069.1 | Uncharacterized protein; Similar to Saccharomyces cerevisiae CAM1 (YPL048W); ancestral locus Anc_8.498 | Uncharacterized protein; Similar to Saccharomyces cerevisiae TEF4 (YKL081W); ancestral locus Anc_2.635 | 0.702 |
| XP_003679479.1 | XP_003683128.1 | XP_003679479.1 | XP_003683128.1 | Uncharacterized protein; Similar to Saccharomyces cerevisiae CAM1 (YPL048W); ancestral locus Anc_8.498 | Uncharacterized protein; Similar to Saccharomyces cerevisiae GCD11 (YER025W); ancestral locus Anc_7.513 | 0.852 |
| XP_003680069.1 | OLA1 | XP_003680069.1 | XP_003681193.1 | Uncharacterized protein; Similar to Saccharomyces cerevisiae TEF4 (YKL081W); ancestral locus Anc_2.635 | Obg-like ATPase 1; Hydrolyzes ATP, and can also hydrolyze GTP with lower efficiency. Has lower affinity for GTP | 0.541 |
| XP_003680069.1 | XP_003679479.1 | XP_003680069.1 | XP_003679479.1 | Uncharacterized protein; Similar to Saccharomyces cerevisiae TEF4 (YKL081W); ancestral locus Anc_2.635 | Uncharacterized protein; Similar to Saccharomyces cerevisiae CAM1 (YPL048W); ancestral locus Anc_8.498 | 0.702 |
