Genes that are sometimes fused into single open reading frames.
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein; Similar to Saccharomyces cerevisiae SER2 (YGR208W); ancestral locus Anc_5.125 (303 aa)
Predicted Functional Partners:
Phosphoserine aminotransferase; Similar to Saccharomyces cerevisiae SER1 (YOR184W); ancestral locus Anc_6.84 (395 aa)
Serine hydroxymethyltransferase; Interconversion of serine and glycine; Belongs to the SHMT family (499 aa)
Serine hydroxymethyltransferase; Interconversion of serine and glycine; Belongs to the SHMT family (469 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae AGX1 (YFL030W); ancestral locus Anc_8.37 (374 aa)
Tryptophan synthase; Similar to Saccharomyces cerevisiae TRP5 (YGL026C); ancestral locus Anc_4.92 (709 aa)
Threonine dehydratase; Similar to Saccharomyces cerevisiae ILV1 (YER086W); ancestral locus Anc_7.367 (569 aa)
Uncharacterized protein (337 aa)
CDP-diacylglycerol--serine O-phosphatidyltransferase; Similar to Saccharomyces cerevisiae CHO1 (YER026C); ancestral locus Anc_3.513; Belongs to the CDP-alcohol phosphatidyltransferase class-I family (274 aa)
Cystathionine beta-synthase; Similar to Saccharomyces cerevisiae CYS4 (YGR155W); ancestral locus Anc_4.69; Belongs to the cysteine synthase/cystathionine beta- synthase family (497 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae RPB4 (YJL140W); ancestral locus Anc_1.208 (236 aa)