Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Groups of genes that are frequently observed in each other's genomic neighborhood.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein; Similar to Saccharomyces cerevisiae TVP15 (YDR100W); ancestral locus Anc_8.244 (138 aa)
Predicted Functional Partners:
Uncharacterized protein; Similar to Saccharomyces cerevisiae TVP18 (YMR071C); ancestral locus Anc_2.534 (167 aa)
Golgi apparatus membrane protein TVP23; Golgi membrane protein involved in vesicular trafficking (196 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae TVP38 (YKR088C); ancestral locus Anc_5.686 (321 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae TLG2 (YOL018C); ancestral locus Anc_1.372; Belongs to the syntaxin family (366 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae HUB1 (YNR032C-A); ancestral locus Anc_6.343 (73 aa)
Protein YIP; Similar to Saccharomyces cerevisiae YIP4 (YGL198W); ancestral locus Anc_8.158 (224 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae GVP36 (YIL041W); ancestral locus Anc_7.221 (338 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae SVP26 (YHR181W); ancestral locus Anc_5.57 (227 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae BOR1 (YNL275W); ancestral locus Anc_1.73 (569 aa)
AP-3 complex subunit delta; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane (939 aa)