Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein; Similar to Saccharomyces cerevisiae DOP1 (YDR141C); ancestral locus Anc_8.313 (1688 aa)
Predicted Functional Partners:
Uncharacterized protein; Similar to Saccharomyces cerevisiae MON2 (YNL297C); ancestral locus Anc_3.61 (1633 aa)
Phospholipid-transporting ATPase; Similar to Saccharomyces cerevisiae NEO1 (YIL048W); ancestral locus Anc_7.234; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily (1141 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae UFD4 (YKL010C); ancestral locus Anc_2.497 (1446 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae YMR010W; ancestral locus Anc_7.112 (383 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae YKL033W-A; ancestral locus Anc_2.544 (242 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae YJR141W; ancestral locus Anc_4.376 (356 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae ARL1 (YBR164C); ancestral locus Anc_8.597; Belongs to the small GTPase superfamily. Arf family (183 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae SNX3 (YOR357C); ancestral locus Anc_7.30 (162 aa)
Proteasome subunit beta; Similar to Saccharomyces cerevisiae PRE4 (YFR050C); ancestral locus Anc_3.574; Belongs to the peptidase T1B family (265 aa)
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (1619 aa)