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XP_003682677.1 protein (Torulaspora delbrueckii) - STRING interaction network
"XP_003682677.1" - Uncharacterized protein in Torulaspora delbrueckii
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
XP_003682677.1Uncharacterized protein; Similar to Saccharomyces cerevisiae DNA2 (YHR164C); ancestral locus Anc_5.75 (1456 aa)    
Predicted Functional Partners:
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (380 aa)
   
 
  0.975
XP_003679034.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae DIN7 (YDR263C) and EXO1 (YOR033C); ancestral locus Anc_5.625 (593 aa)
   
 
  0.974
PIF1
ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5’-3’ DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA [...] (949 aa)
   
 
  0.954
XP_003679234.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae SGS1 (YMR190C); ancestral locus Anc_6.278 (1364 aa)
     
 
  0.952
XP_003682380.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae CTF4 (YPR135W); ancestral locus Anc_3.473 (917 aa)
     
 
  0.950
XP_003682247.1
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single-stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism (616 aa)
     
 
  0.930
XP_003679501.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae RMI1 (YPL024W); ancestral locus Anc_8.475 (223 aa)
     
 
  0.912
XP_003682560.1
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5’-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3’-OH DNA strand (652 aa)
     
 
  0.907
XP_003680638.1
Uncharacterized protein; Similar to Saccharomyces cerevisiae MEC1 (YBR136W); ancestral locus Anc_3.401 (2371 aa)
     
 
  0.904
XP_003680304.1
DNA ligase; Similar to Saccharomyces cerevisiae CDC9 (YDL164C); ancestral locus Anc_7.343 (705 aa)
     
 
  0.897
Your Current Organism:
Torulaspora delbrueckii
NCBI taxonomy Id: 4950
Other names: Candida colliculosa, Saccharomyces delbrueckii, Saccharomyces fermentati, Saccharomyces rosei, T. delbrueckii, Torulaspora delbrueckii, Torulaspora sp. R3DFM2, WM 821
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