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GET3 protein (Torulaspora delbrueckii) - STRING interaction network
"GET3" - Hypothetical protein in Torulaspora delbrueckii
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
GET3Hypothetical protein; ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for ins [...] (353 aa)    
Predicted Functional Partners:
GET2
Hypothetical protein; Required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Together with GET1, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER (310 aa)
       
  0.982
GET1
Hypothetical protein; Required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Together with GET2, acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. The GET complex cooperates with the HDEL receptor ERD2 to mediate the ATP-dependent retrieval of resident ER proteins that contain a C-terminal H-D-E-L retention signal from the Golgi to the ER (224 aa)
       
  0.980
XP_003682991.1
Hypothetical protein (306 aa)
       
 
  0.969
XP_003681528.1
Hypothetical protein (197 aa)
       
 
  0.945
XP_003681596.1
Hypothetical protein (515 aa)
     
  0.754
XP_003680965.1
Hypothetical protein (489 aa)
     
  0.730
XP_003680359.1
Hypothetical protein (368 aa)
       
 
  0.727
XP_003680278.1
Hypothetical protein (88 aa)
     
  0.700
XP_003683026.1
Hypothetical protein (343 aa)
     
 
  0.653
XP_003678685.1
Hypothetical protein (76 aa)
     
 
  0.622
Your Current Organism:
Torulaspora delbrueckii
NCBI taxonomy Id: 4950
Other names: Candida colliculosa, Saccharomyces fermentati, Saccharomyces rosei, T. delbrueckii, Torulaspora, Torulaspora delbrueckii
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