Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Uncharacterized protein; Similar to Saccharomyces cerevisiae DOT5 (YIL010W); ancestral locus Anc_7.126 (354 aa)
Predicted Functional Partners:
Uncharacterized protein; Similar to Saccharomyces cerevisiae TSA2 (YDR453C) and TSA1 (YML028W); ancestral locus Anc_5.569 (196 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae AHP1 (YLR109W); ancestral locus Anc_8.300 (176 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae PRX1 (YBL064C); ancestral locus Anc_7.388 (249 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae GLR1 (YPL091W); ancestral locus Anc_8.568; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family (484 aa)
Thioredoxin reductase; Similar to Saccharomyces cerevisiae TRR1 (YDR353W) and TRR2 (YHR106W); ancestral locus Anc_5.411; Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family (342 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae MRPL7 (YDR237W); ancestral locus Anc_8.461 (294 aa)
Uncharacterized protein; Similar to Saccharomyces cerevisiae YNL122C; ancestral locus Anc_2.151 (93 aa)
Uncharacterized protein; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis (549 aa)
Sulfiredoxin; Similar to Saccharomyces cerevisiae SRX1 (YKL086W); ancestral locus Anc_2.642 (126 aa)
Uncharacterized protein; Ancestral locus Anc_3.54 (180 aa)