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XP_499663.1 protein (Yarrowia lipolytica) - STRING interaction network
"XP_499663.1" - YALI0A01760p in Yarrowia lipolytica
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second shell of interactors
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some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
XP_499663.1YALI0A01760p (426 aa)    
Predicted Functional Partners:
CTU2
YALI0B10263p; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). May act by forming a heterodimer with NCS6 that ligates sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation (424 aa)
     
  0.944
XP_501544.1
YALI0C07128p (553 aa)
   
 
  0.709
XP_501096.1
YALI0B19382p (1850 aa)
   
   
  0.694
ARO1
YALI0F12639p; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis (1556 aa)
     
 
  0.692
UBA4
YALI0C18095p; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl- adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequently, a transient disulfide bond [...] (396 aa)
     
 
  0.579
URM1
YALI0E19481p; Acts as a sulfur carrier required for 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Serves as sulfur donor in tRNA 2- thiolation reaction by being thiocarboxylated (-COSH) at its C- terminus by the MOCS3 homolog UBA4. The sulfur is then transferred to tRNA to form 2-thiolation of mcm(5)S(2)U. Prior mcm(5) tRNA modification by the elongator complex is required for 2- thiolation. Also acts as a ubiquitin-like protein (UBL) that is covalently conjugated via an isopeptide bond to lysine residues of target proteins such a [...] (99 aa)
       
  0.506
XP_503720.1
YALI0E09108p (538 aa)
     
  0.493
XP_502366.1
YALI0D03509p (460 aa)
     
 
  0.484
XP_500430.1
YALI0B02574p (763 aa)
     
 
  0.484
XP_500384.1
YALI0B01386p (708 aa)
     
 
  0.484
Your Current Organism:
Yarrowia lipolytica
NCBI taxonomy Id: 4952
Other names: Candida lipolytica, Dipodascaceae, Mycotorula lipolytica, Y. lipolytica, Yarrowia, Yarrowia lipolytica
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